Gene Editing by Ferrying of CRISPR/Cas Ribonucleoprotein Complexes in Enveloped Virus-Derived Particles

JH Janns, JG Mikkelsen - Human Gene Therapy, 2024 - liebertpub.com
The invention of next-generation CRISPR/Cas gene editing tools, like base and prime
editing, for correction of gene variants causing disease, has created hope for in vivo use in …

Cell-specific delivery of CRISPR-Cas9 with pseudotyped lentiviral particles: Just change the envelope

Á Covo-Vergara, L Salaberry, N Silva-Pilipich… - … Therapy Nucleic Acids, 2024 - cell.com
The manuscript by Nielsen et al. describes a strategy based on pseudotyping lentivirus-
derived nanoparticles (LVNPs) to deliver CRISPR-Cas9 ribonucleoprotein (RNP) complexes …

DESBLOQUEANDO A CURA DO HIV: O POTENCIAL DO CRISPR-CAS9 PARA MODIFICAR GENES E ELIMINAR RESERVATÓRIOS VIRAIS

BC Burille, HSL Neto, MM Machado… - Brazilian Journal of …, 2024 - bjihs.emnuvens.com.br
Resumo O HIV (Vírus da Imunodeficiência Humana) continua sendo um dos maiores
desafios da saúde pública global, afetando milhões de pessoas em todo o mundo. Embora …