Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases
S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …
challenges to public health security and the global economy. The development and …
Virus-like particles as a highly efficient vaccine platform: diversity of targets and production systems and advances in clinical development
N Kushnir, SJ Streatfield, V Yusibov - Vaccine, 2012 - Elsevier
Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …
soluble recombinant antigens by stronger protective immunogenicity associated with the …
VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain
A Marzi, SJ Robertson, E Haddock, F Feldmann… - Science, 2015 - science.org
The latest Ebola virus (EBOV) epidemic spread rapidly through Guinea, Sierra Leone, and
Liberia, creating a global public health crisis and accelerating the assessment of …
Liberia, creating a global public health crisis and accelerating the assessment of …
Natural-killer cells and dendritic cells:“l'union fait la force”
Several recent publications have focused on the newly described interactions between
natural-killer (NK) cells and dendritic cells (DCs). Activated NK cells induce DC maturation …
natural-killer (NK) cells and dendritic cells (DCs). Activated NK cells induce DC maturation …
Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis
N Wauquier, P Becquart, C Padilla… - PLoS neglected …, 2010 - journals.plos.org
Background Ebolavirus species Zaire (ZEBOV) causes highly lethal hemorrhagic fever,
resulting in the death of 90% of patients within days. Most information on immune responses …
resulting in the death of 90% of patients within days. Most information on immune responses …
Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1
The elimination of viruses and tumors by natural killer cells is mediated by specific natural
killer cell receptors. To study the in vivo function of a principal activating natural killer cell …
killer cell receptors. To study the in vivo function of a principal activating natural killer cell …
Natural killer cells as an initial defense against pathogens
MB Lodoen, LL Lanier - Current opinion in immunology, 2006 - Elsevier
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …
[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Effective post-exposure treatment of Ebola infection
H Feldmann, SM Jones, KM Daddario-DiCaprio… - PLoS …, 2007 - journals.plos.org
Ebola viruses are highly lethal human pathogens that have received considerable attention
in recent years due to an increasing re-emergence in Central Africa and a potential for use …
in recent years due to an increasing re-emergence in Central Africa and a potential for use …
Molecular mechanisms of Ebola virus pathogenesis: focus on cell death
Ebola virus (EBOV) belongs to the Filoviridae family and is responsible for a severe disease
characterized by the sudden onset of fever and malaise accompanied by other non-specific …
characterized by the sudden onset of fever and malaise accompanied by other non-specific …