The renin‐angiotensin system: a link between obesity, inflammation and insulin resistance

NS Kalupahana, N Moustaid‐Moussa - Obesity reviews, 2012 - Wiley Online Library
The renin‐angiotensin system (RAS) is classically known for its role in regulation of blood
pressure, fluid and electrolyte balance. Recently, several local RASs in organs such as …

Early postnatal alteration of body composition in preterm and small-for-gestational-age infants: implications of catch-up fat

T Okada, S Takahashi, N Nagano, K Yoshikawa… - Pediatric …, 2015 - nature.com
The concept of the developmental origins of health and disease is based on studies by
Barker et al. They proposed a hypothesis that undernutrition in utero permanently changes …

[HTML][HTML] Genetic evidence for causal relationships between maternal obesity-related traits and birth weight

J Tyrrell, RC Richmond, TM Palmer, B Feenstra… - Jama, 2016 - jamanetwork.com
Importance Neonates born to overweight or obese women are larger and at higher risk of
birth complications. Many maternal obesity-related traits are observationally associated with …

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization

DM Evans, GH Moen, LD Hwang… - International journal …, 2019 - academic.oup.com
Background There is considerable interest in estimating the causal effect of a range of
maternal environmental exposures on offspring health-related outcomes. Previous attempts …

Mechanisms in endocrinology: epigenetic modifications and gestational diabetes: a systematic review of published literature

GH Moen, C Sommer, RB Prasad… - European journal of …, 2017 - academic.oup.com
Objective To summarize the current knowledge on epigenetic alterations in mother and
offspring subjected to gestational diabetes (GDM) and indicate future topics for research …

Parental genetic effects on the offspring's phenotype without transmission of the gene itself—pathophysiology and clinical evidence

X Zhang, B Hocher - American Journal of Physiology-Cell …, 2024 - journals.physiology.org
Parental genes can influence the phenotype of their offspring through genomic-epigenomic
interactions even without the direct inheritance of specific parental genotypes. Maternal …

Renin-angiotensin-aldosterone genotype influences ventricular remodeling in infants with single ventricle

S Mital, WK Chung, SD Colan, LA Sleeper, C Manlhiot… - Circulation, 2011 - Am Heart Assoc
Background—We investigated the effect of polymorphisms in the renin-angiotensin-
aldosterone system (RAAS) genes on ventricular remodeling, growth, renal function, and …

Low birth weight, a risk factor for diseases in later life, is a surrogate of insulin resistance at birth

M Tian, C Reichetzeder, J Li, B Hocher - Journal of hypertension, 2019 - journals.lww.com
Low birth weight (LBW) is associated with diseases in adulthood. The birthweight attributed
risk is independent of confounding such as gestational age, sex of the newborn but also …

Role of mineralocorticoid receptor in insulin resistance

R Garg, GK Adler - Current Opinion in Endocrinology, Diabetes …, 2012 - journals.lww.com
Role of mineralocorticoid receptor in insulin resistance : Current Opinion in Endocrinology,
Diabetes and Obesity Role of mineralocorticoid receptor in insulin resistance : Current Opinion …

The potential impact of the fetal genotype on maternal blood pressure during pregnancy

CJ Petry, K Beardsall, DB Dunger - Journal of Hypertension, 2014 - journals.lww.com
The heritability of pregnancy-induced hypertension (encompassing both gestational
hypertension and preeclampsia) is around 0.47, suggesting that there is a genetic …