Mechanisms of metabolic reprogramming in cancer cells supporting enhanced growth and proliferation
C Schiliro, BL Firestein - Cells, 2021 - mdpi.com
Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …
and proliferation. These metabolic alterations include (1) a shift from oxidative …
Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer
A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …
Ketone bodies in neurological diseases: focus on neuroprotection and underlying mechanisms
H Yang, W Shan, F Zhu, J Wu, Q Wang - Frontiers in neurology, 2019 - frontiersin.org
There is growing evidence that ketone bodies, which are derived from fatty acid oxidation
and usually produced in fasting state or on high-fat diets have broad neuroprotective effects …
and usually produced in fasting state or on high-fat diets have broad neuroprotective effects …
Targeting the Warburg effect for cancer treatment: Ketogenic diets for management of glioma
A Poff, AP Koutnik, KM Egan, S Sahebjam… - Seminars in Cancer …, 2019 - Elsevier
Gliomas are a highly heterogeneous tumor, refractory to treatment and the most frequently
diagnosed primary brain tumor. Although the current WHO grading system (2016) …
diagnosed primary brain tumor. Although the current WHO grading system (2016) …
The evolution of ketosis: potential impact on clinical conditions
Ketone bodies are small compounds derived from fatty acids that behave as an alternative
mitochondrial energy source when insulin levels are low, such as during fasting or …
mitochondrial energy source when insulin levels are low, such as during fasting or …
Mitochondrial substrate-level phosphorylation as energy source for glioblastoma: review and hypothesis
C Chinopoulos, TN Seyfried - ASN neuro, 2018 - journals.sagepub.com
Glioblastoma multiforme (GBM) is the most common and malignant of the primary adult brain
cancers. Ultrastructural and biochemical evidence shows that GBM cells exhibit …
cancers. Ultrastructural and biochemical evidence shows that GBM cells exhibit …
Ketogenic diet and multiple health outcomes: an umbrella review of meta-analysis
S Chen, X Su, Y Feng, R Li, M Liao, L Fan, J Liu… - Nutrients, 2023 - mdpi.com
Numerous studies have examined the effects of ketogenic diets (KD) on health-related
outcomes through meta-analyses. However, the presence of biases may compromise the …
outcomes through meta-analyses. However, the presence of biases may compromise the …
Nutritional impact on metabolic homeostasis and brain health
L Carneiro, L Pellerin - Frontiers in Neuroscience, 2022 - frontiersin.org
Aging in modern societies is often associated with various diseases including metabolic and
neurodegenerative disorders. In recent years, researchers have shown that both …
neurodegenerative disorders. In recent years, researchers have shown that both …
Current research trends, hotspots, and frontiers of medical nutrition therapy on cancer: a bibliometric analysis
H Xia, L Wang, H Wang - Frontiers in Oncology, 2023 - frontiersin.org
Background There is a high prevalence of malnutrition in cancer patients, which seriously
affects the anti-cancer therapy effect and outcomes, causing a huge disease burden …
affects the anti-cancer therapy effect and outcomes, causing a huge disease burden …
Carbohydrate nutrition and the risk of cancer
CA Maino Vieytes, HM Taha, AA Burton-Obanla… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review This review summarizes a selection of epidemiologic research
assessing the associations between carbohydrate intake and cancer incidence and survival …
assessing the associations between carbohydrate intake and cancer incidence and survival …