[HTML][HTML] Glutathione in the Brain

K Aoyama - International journal of molecular sciences, 2021 - mdpi.com
Glutathione (GSH) is the most abundant non-protein thiol, and plays crucial roles in the
antioxidant defense system and the maintenance of redox homeostasis in neurons. GSH …

Sulfhydryl groups as targets of mercury toxicity

OP Ajsuvakova, AA Tinkov, M Aschner… - Coordination chemistry …, 2020 - Elsevier
The present study addresses existing data on the affinity and conjugation of sulfhydryl (thiol;-
SH) groups of low-and high-molecular-weight biological ligands with mercury (Hg). The …

The role of glutathione reductase and related enzymes on cellular redox homoeostasis network

N Couto, J Wood, J Barber - Free radical biology and medicine, 2016 - Elsevier
In this review article we examine the role of glutathione reductase in the regulation,
modulation and maintenance of cellular redox homoeostasis. Glutathione reductase is …

[PDF][PDF] Small-molecule fluorescent probes for imaging and detection of reactive oxygen, nitrogen, and sulfur species in biological systems

X Jiao, Y Li, J Niu, X Xie, X Wang, B Tang - Anal. Chem, 2018 - tangb.sdnu.edu.cn
Small-Molecule Fluorescent Probes for Imaging and Detection of Reactive Oxygen, Nitrogen,
and Sulfur Species in Biological Syste Page 1 Small-Molecule Fluorescent Probes for Imaging …

Regulators of the transsulfuration pathway

JI Sbodio, SH Snyder, BD Paul - British journal of …, 2019 - Wiley Online Library
The transsulfuration pathway is a metabolic pathway where transfer of sulfur from
homocysteine to cysteine occurs. The pathway leads to the generation of several sulfur …

Cysteine metabolism in neuronal redox homeostasis

BD Paul, JI Sbodio, SH Snyder - Trends in pharmacological sciences, 2018 - cell.com
Besides its essential role in protein synthesis, cysteine plays vital roles in redox
homeostasis, being a component of the major antioxidant glutathione (GSH) and a potent …

A ratiometric photoacoustic probe with a reversible response to hydrogen sulfide and hydroxyl radicals for dynamic imaging of liver inflammation

L Wu, W Zeng, Y Ishigaki, J Zhang, H Bai… - Angewandte Chemie …, 2022 - Wiley Online Library
Reversible imaging probes that allow for the dynamic visualization of the redox cycle
between hydroxyl radical (⋅ OH) and hydrogen sulfide (H2S) are vital to probe the redox …

[HTML][HTML] Redox regulation in metabolic programming and inflammation

HR Griffiths, D Gao, C Pararasa - Redox biology, 2017 - Elsevier
Energy metabolism and redox state are intrinsically linked. In order to mount an adequate
immune response, cells must have an adequate and rapidly available energy resource to …

The dual role of Reactive Oxygen Species in autoimmune and inflammatory diseases: evidence from preclinical models

MH Hoffmann, HR Griffiths - Free radical biology and medicine, 2018 - Elsevier
Reactive oxygen species (ROS) are created in cells during oxidative phosphorylation by the
respiratory chain in the mitochondria or by the family of NADPH oxidase (NOX) complexes …

[HTML][HTML] Cysteine, glutathione, and thiol redox balance in astrocytes

GJ McBean - Antioxidants, 2017 - mdpi.com
This review discusses the current understanding of cysteine and glutathione redox balance
in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte …