Olfactory dysfunction in aging and neurodegenerative diseases

X Dan, N Wechter, S Gray, JG Mohanty… - Ageing research …, 2021 - Elsevier
Alterations in olfactory functions are proposed to be early biomarkers for neurodegeneration.
Many neurodegenerative diseases are age-related, including two of the most common …

Neurons, nose, and neurodegenerative diseases: olfactory function and cognitive impairment

I Fatuzzo, GF Niccolini, F Zoccali, L Cavalcanti… - International Journal of …, 2023 - mdpi.com
Olfactory capacity declines with aging, but increasing evidence shows that smell dysfunction
is one of the early signs of prodromal neurodegenerative diseases such as Alzheimer's and …

A systematic review and methodological analysis of EEG-based biomarkers of Alzheimer's disease

A Modir, S Shamekhi, P Ghaderyan - Measurement, 2023 - Elsevier
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders in the
world. Although there is no known cure for it at the present, preventive drug trials and …

The olfactory system as marker of neurodegeneration in aging, neurological and neuropsychiatric disorders

N Bhatia-Dey, T Heinbockel - … of environmental research and public health, 2021 - mdpi.com
Research studies that focus on understanding the onset of neurodegenerative pathology
and therapeutic interventions to inhibit its causative factors, have shown a crucial role of …

The Current Status and Challenges of Olfactory Dysfunction Study in Alzheimer's Disease

W Liao, Y Wang, J Li, D Huang, W Cheng… - Ageing Research …, 2024 - Elsevier
Olfactory functioning involves multiple cognitive processes and the coordinated actions of
various neural systems. Any disruption at any stage of this process may result in olfactory …

Network synchronization deficits caused by dementia and Alzheimer's disease serve as topographical biomarkers: a pilot study

MJ Sedghizadeh, H Aghajan, Z Vahabi… - Brain Structure and …, 2022 - Springer
Mild cognitive impairment (MCI) is known as an early stage of cognitive decline. Amnestic
MCI (aMCI) is considered as the preliminary stage of dementia which may progress to …

Uncovering the correlation between COVID-19 and neurodegenerative processes: Toward a new approach based on EEG entropic analysis

A Cataldo, S Criscuolo, E De Benedetto, A Masciullo… - Bioengineering, 2023 - mdpi.com
COVID-19 is an ongoing global pandemic caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) virus. Although it primarily attacks the respiratory tract …

Odor identification score as an alternative method for early identification of amyloidogenesis in Alzheimer's disease

Y Igeta, I Hemmi, K Yuyama, Y Ouchi - Scientific Reports, 2024 - nature.com
A simple screening test to identify the early stages of Alzheimer's disease (AD) is urgently
needed. We investigated whether odor identification impairment can be used to differentiate …

Using chemosensory-induced EEG signals to identify patients with de novo Parkinson's disease

BO Olcay, F Onay, GA Öztürk, A Öniz… - … Signal Processing and …, 2024 - Elsevier
Objective Parkinson's disease (PD) patients generally exhibit an olfactory loss. Hence,
psychophysical or electrophysiological tests are used for diagnosis. However, these tests …

Behavior of olfactory-related frontal lobe oscillations in Alzheimer's disease and MCI: A pilot study

SN Fatemi, H Aghajan, Z Vahabi, A Afzal… - International Journal of …, 2022 - Elsevier
Abstract Slow-gamma (35-45 Hz) phase synchronization and the coupling between slow-
gamma and low-frequency theta oscillations (4–8 Hz) are closely related to memory retrieval …