Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels comprise a small
subfamily of proteins within the superfamily of pore-loop cation channels. In mammals, the …

Highlights•Hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels are
involved in multiple physiological processes.•HCN channels are excellent targets of various …

Acquisition, analysis and simulation of electrophysiological properties of the nervous system
require multiple software packages. This makes it difficult to conserve experimental …

Neurons in the medial entorhinal cortex exhibit a grid-like spatial pattern of spike rates that
has been proposed to represent a neural code for path integration. To understand how grid …

The hippocampal formation is critically involved in learning and memory and contains a
large proportion of neurons encoding aspects of the organism's spatial surroundings. In the …

Ketamine has important anesthetic, analgesic, and psychotropic actions. It is widely believed
that NMDA receptor inhibition accounts for ketamine actions, but there remains a dearth of …

The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are voltage-gated
ion channels that critically modulate neuronal activity. Four HCN subunits (HCN1–4) have …

The hyperpolarization‐activated cyclic nucleotide‐gated (HCN) channels belong to the
superfamily of voltage‐gated potassium ion channels. They are, however, activated by …

Differences in behavioral roles, anatomical connectivity, and gene expression patterns in the
dorsal, intermediate, and ventral regions of the hippocampus are well characterized …

Hyperpolarization-activated cation nonselective 1 (HCN1) plasticity in entorhinal cortical
(EC) and hippocampal pyramidal cell dendrites is a salient feature of temporal lobe …