Osteoarthritis (OA) and rheumatoid arthritis (RA) are both debilitating diseases that cause
significant morbidity in the US population. Extracellular vesicles (EVs), including exosomes …

The transfer of molecules between cells during cognate immune cell interactions has been
reported, and recently a novel mechanism of transfer of proteins and genetic material such …

In response to myocardial infarction (MI), cardiac macrophages regulate inflammation and
scar formation. We hypothesized that macrophages undergo polarization state changes over …

Neutrophils recognize particulate substrates of microbial or endogenous origin and react by
sequestering the cargo via phagocytosis or by releasing neutrophil extracellular traps …

BACKGROUND: Leukotrienes (LTs) are potent proinflammatory lipid mediators with key
roles in the pathogenesis of asthma and inflammation. Recently, nanovesicles (exosomes) …

Cell-derived extracellular vesicles (EVs), present in synovial fluid and cartilage extracellular
matrix (ECM), are involved in joint development and in the regulation of joint homeostasis …

Protein kinase CK2 (formerly referred to as casein kinase II) is an evolutionary conserved,
ubiquitous protein kinase. There are two paralog catalytic subunits, ie alpha (A1) and …

This study was performed to identify the origin of the ascites-derived exosomes from patients
with ovarian cancer and to observe the effect of exosomes on anti-tumor immunity …

In recent years exosomes have emerged as potent stimulators of immune responses and as
agents for cancer therapy. Exosomes can carry a broad variety of immunostimulatory …

Gain of chromosome 6p is a consistent feature of advanced melanomas. However, the
identity of putative oncogene (s) associated with this amplification has remained elusive …