[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
clear pathogens. However, their excessive release is the main cause of hyperinflammation …
Epigenetic regulation in AKI and kidney repair: mechanisms and therapeutic implications
C Guo, G Dong, X Liang, Z Dong - Nature Reviews Nephrology, 2019 - nature.com
Acute kidney injury (AKI) is a major public health concern associated with high morbidity and
mortality. Despite decades of research, the pathogenesis of AKI remains incompletely …
mortality. Despite decades of research, the pathogenesis of AKI remains incompletely …
[HTML][HTML] CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14
BK Patterson, H Seethamraju, K Dhody… - International Journal of …, 2021 - Elsevier
Objective Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is
now a global pandemic. Emerging results indicate a dysregulated immune response. Given …
now a global pandemic. Emerging results indicate a dysregulated immune response. Given …
Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
JW Shih, WF Chiang, ATH Wu, MH Wu… - Nature …, 2017 - nature.com
Long noncoding RNAs (lncRNAs) have been implicated in hypoxia/HIF-1-associated cancer
progression through largely unknown mechanisms. Here we identify MIR31HG as a hypoxia …
progression through largely unknown mechanisms. Here we identify MIR31HG as a hypoxia …
[HTML][HTML] Noncoding RNAs in acute kidney injury
T Brandenburger, AS Somoza, Y Devaux… - Kidney International, 2018 - Elsevier
Acute kidney injury (AKI) is an important health issue concerning∼ 50% of patients treated
in intensive care units. AKI mainly occurs after sepsis, acute ischemia, nephrotoxicity, or …
in intensive care units. AKI mainly occurs after sepsis, acute ischemia, nephrotoxicity, or …
Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …
mmu-lncRNA 121686/hsa-lncRNA 520657 induced by METTL3 drive the progression of AKI by targeting miR-328-5p/HtrA3 signaling axis
J Pan, Y Xie, H Li, X Li, J Chen, X Liu, J Zhou, X Tang… - Molecular Therapy, 2022 - cell.com
The pathogenesis of acute kidney injury (AKI) is still not fully understood, and effective
interventions are lacking. Here, we explored whether methyltransferase 3 (METTL3) was …
interventions are lacking. Here, we explored whether methyltransferase 3 (METTL3) was …
Disruption of the CCL5/RANTES-CCR5 pathway restores immune homeostasis and reduces plasma viral load in critical COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), is now pandemic with nearly three million cases …
coronavirus disease 2019 (COVID-19), is now pandemic with nearly three million cases …
[HTML][HTML] Non-coding RNAs in kidney injury and repair
Z Liu, Y Wang, S Shu, J Cai… - American Journal of …, 2019 - journals.physiology.org
Acute kidney injury (AKI) is a major kidney disease featured by a rapid decline of renal
function. Pathologically, AKI is characterized by tubular epithelial cell injury and death …
function. Pathologically, AKI is characterized by tubular epithelial cell injury and death …
Long non-coding RNAs in kidney disease
Non-coding RNA species contribute more than 90% of all transcripts and have gained
increasing attention in the last decade. One of the most recent members of this group are …
increasing attention in the last decade. One of the most recent members of this group are …