Superoxide dismutases: role in redox signaling, vascular function, and diseases

T Fukai, M Ushio-Fukai - Antioxidants & redox signaling, 2011 - liebertpub.com
Excessive reactive oxygen species Revised abstract, especially superoxide anion (O2•−),
play important roles in the pathogenesis of many cardiovascular diseases, including …

Nitric oxide and peroxynitrite in health and disease

P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007 - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

[HTML][HTML] Cardiac autonomic neuropathy in patients with diabetes mellitus

G Dimitropoulos, AA Tahrani… - World journal of …, 2014 - ncbi.nlm.nih.gov
Cardiac autonomic neuropathy (CAN) is an often overlooked and common complication of
diabetes mellitus. CAN is associated with increased cardiovascular morbidity and mortality …

Neurovascular regulation in the normal brain and in Alzheimer's disease

C Iadecola - Nature Reviews Neuroscience, 2004 - nature.com
The structural and functional integrity of the brain depends on the delicate balance between
substrate delivery through blood flow and energy demands imposed by neural activity …

Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice

JS Johansen, AK Harris, DJ Rychly, A Ergul - Cardiovascular diabetology, 2005 - Springer
Cardiovascular complications, characterized by endothelial dysfunction and accelerated
atherosclerosis, are the leading cause of morbidity and mortality associated with diabetes …

The therapeutic potential of poly (ADP-ribose) polymerase inhibitors

L Virag, C Szabó - Pharmacological reviews, 2002 - ASPET
Poly (ADP-ribose) polymerase-1 (PARP-1) is a member of the PARP enzyme family
consisting of PARP-1 and several recently identified novel poly (ADP-ribosylating) enzymes …

New insights on oxidative stress and diabetic complications may lead to a “causal” antioxidant therapy

A Ceriello - Diabetes care, 2003 - Am Diabetes Assoc
Evidence implicates hyperglycemia-derived oxygen free radicals as mediators of diabetic
complications. However, intervention studies with classic antioxidants, such as vitamin E …

[HTML][HTML] Arginase: a critical regulator of nitric oxide synthesis and vascular function

W Durante, FK Johnson, RA Johnson - Clinical and experimental …, 2007 - ncbi.nlm.nih.gov
ARGINASE: A CRITICAL REGULATOR OF NITRIC OXIDE SYNTHESIS AND VASCULAR
FUNCTION - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

[HTML][HTML] Diabetes and alpha lipoic acid

I Laher - Frontiers in pharmacology, 2011 - frontiersin.org
Diabetes mellitus is a multi-faceted metabolic disorder where there is increased oxidative
stress that contributes to the pathogenesis of this debilitating disease. This has prompted …

Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives

VL Fisher, AA Tahrani - … syndrome and obesity: targets and therapy, 2017 - Taylor & Francis
Cardiac autonomic neuropathy (CAN) is a common and often-underdiagnosed complication
of diabetes mellitus (DM). CAN is associated with increased mortality, cardiovascular …