Contrary to the long-held view that most humans harbour only identical mitochondrial
genomes, deep resequencing has uncovered unanticipated extreme genetic variation within …

Mitochondria are key to energy conversion in virtually all eukaryotes. Intriguingly, despite
billions of years of evolution inside the eukaryote, mitochondria have retained their own …

Mitochondria perform an array of functions, many of which involve interactions with gene
products encoded by the nucleus. These mitochondrial functions, particularly those involving …

Evolutionary theory proposes that maternal inheritance of mitochondria will facilitate the
accumulation of mitochondrial DNA (mtDNA) mutations that are harmful to males but benign …

Arguably, the most important discovery in the biology of aging to date was that simply
reducing food intake extended life and improved many aspects of health in a diversity of …

The mitonuclear genome is the most successful co-evolved mutualism in the history of life on
Earth. The cross-talk between the mitochondrial and nuclear genomes has been shaped by …

Abstract Drosophila melanogaster Meigen (Diptera: Drosophilidae) is a key model insect for
studying life span and aging. Many laboratory strains of D. melanogaster are currently used …

Mitochondria evolved from a union of microbial cells belonging to distinct lineages that were
likely anaerobic. The evolution of eukaryotes required a massive reorganization of the 2 …

Organismal fitness is partly determined by how well the nutritional intake matches sex-
specific metabolic requirements. Metabolism itself is underpinned by complex genomic …

Biocontrol techniques that impair reproductive capacity of insect pests provide opportunities
to control the dynamics of their populations while minimizing collateral damage to non …