Bone stress injuries

T Hoenig, KE Ackerman, BR Beck… - Nature Reviews …, 2022 - nature.com
Bone stress injuries, including stress fractures, are overuse injuries that lead to substantial
morbidity in active individuals. These injuries occur when excessive repetitive loads are …

Oxidative stress and natural antioxidants in osteoporosis: Novel preventive and therapeutic approaches

G Marcucci, V Domazetovic, C Nediani, J Ruzzolini… - Antioxidants, 2023 - mdpi.com
This review reports in detail the cellular and molecular mechanisms which regulate the bone
remodeling process in relation to oxidative stress (OS), inflammatory factors, and estrogen …

Update on the effects of microgravity on the musculoskeletal system

OJ Juhl IV, EG Buettmann, MA Friedman… - npj …, 2021 - nature.com
With the reignited push for manned spaceflight and the development of companies focused
on commercializing spaceflight, increased human ventures into space are inevitable …

Guided bone regeneration using barrier membrane in dental applications

K Kim, Y Su, AJ Kucine, K Cheng… - ACS Biomaterials Science …, 2023 - ACS Publications
Guided bone regeneration (GBR) is a widely used technique in preclinical and clinical
studies due to its predictability. Its main purpose is to prevent the migration of soft tissue into …

The roles of osteocytes in alveolar bone destruction in periodontitis

X Huang, M Xie, Y Xie, F Mei, X Lu, X Li… - Journal of Translational …, 2020 - Springer
Periodontitis, a bacterium-induced inflammatory disease that is characterized by alveolar
bone loss, is highly prevalent worldwide. Elucidating the underlying mechanisms of alveolar …

Osteoimmunology in periodontitis: local proteins and compounds to alleviate periodontitis

K Sirisereephap, T Maekawa, H Tamura… - International Journal of …, 2022 - mdpi.com
Periodontitis is one of the most common oral diseases resulting in gingival inflammation and
tooth loss. Growing evidence indicates that it results from dysbiosis of the oral microbiome …

Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin

JS Wang, T Kamath, CM Mazur… - Nature …, 2021 - nature.com
Some osteoblasts embed within bone matrix, change shape, and become dendrite-bearing
osteocytes. The circuitry that drives dendrite formation during “osteocytogenesis” is poorly …

Osteocytes and bone metastasis

MA Riquelme, ER Cardenas, JX Jiang - Frontiers in endocrinology, 2020 - frontiersin.org
Bone is the most frequent site of breast cancer and prostate cancer metastasis, and one of
the most common sites of metastasis for many solid tumors. Once cancer cells colonize in …

Control of bone matrix properties by osteocytes

A Creecy, JG Damrath, JM Wallace - Frontiers in endocrinology, 2021 - frontiersin.org
Osteocytes make up 90–95% of the cellular content of bone and form a rich dendritic
network with a vastly greater surface area than either osteoblasts or osteoclasts. Osteocytes …

SP7: From bone development to skeletal disease

JS Wang, N Tokavanich, MN Wein - Current osteoporosis reports, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to summarize the different roles of
the transcription factor SP7 in regulating bone formation and remodeling, discuss current …