Layered mechanisms regulating the human mitochondrial NAD+ transporter SLC25A51

S Goyal, XA Cambronne - Biochemical Society Transactions, 2023 - portlandpress.com
SLC25A51 is the primary mitochondrial NAD+ transporter in humans and controls many
local reactions by mediating the influx of oxidized NAD+. Intriguingly, SLC25A51 lacks …

The effects of cardiolipin on the structural dynamics of the mitochondrial ADP/ATP carrier in its cytosol-open state

Q Yi, S Yao, B Ma, X Cang - Journal of Lipid Research, 2022 - ASBMB
Cardiolipin (CL) has been shown to play a crucial role in regulating the function of proteins
in the inner mitochondrial membrane. As the most abundant protein of the inner …

Structural and energetic insights into the selective inhibition of PKMYT1 against WEE1

X Qi, G Li, J Liu, L Mou, Y Zhang, S Guo… - Journal of …, 2024 - Taylor & Francis
Protein kinase, membrane-associated tyrosine/threonine 1 (PKMYT1), a member of the WEE
family and responsible for the regulation of CDK1 phosphorylation, has been considered a …

Evidence for non-essential salt bridges in the M-gates of mitochondrial carrier proteins

DV Miniero, M Monné, MA Di Noia, L Palmieri… - International Journal of …, 2022 - mdpi.com
Mitochondrial carriers, which transport metabolites, nucleotides, and cofactors across the
mitochondrial inner membrane, have six transmembrane α-helices enclosing a translocation …

In Silico Analysis of the Structural Dynamics and Substrate Recognition Determinants of the Human Mitochondrial Carnitine/Acylcarnitine SLC25A20 Transporter

A Pasquadibisceglie, V Quadrotta… - International Journal of …, 2023 - mdpi.com
The Carnitine-Acylcarnitine Carrier is a member of the mitochondrial Solute Carrier Family
25 (SLC25), known as SLC25A20, involved in the electroneutral exchange of acylcarnitine …

[HTML][HTML] Praseodymium trivalent ion is an effective inhibitor of mitochondrial basic amino acids and carnitine/acylcarnitine carriers

G Incampo, N Giangregorio, N Gambacorta… - … et Biophysica Acta (BBA …, 2022 - Elsevier
We herein report the identification of the lantanide praseodymium trivalent ion Pr 3+ as
inhibitor of mitochondrial transporters for basic amino acids and phylogenetically related …

[PDF][PDF] BBA-Bioenergetics

G Incampo, N Giangregorio, N Gambacorta, O Nicolotti… - dibest2.unical.it
We herein report the identification of the lantanide praseodymium trivalent ion Pr3+ as
inhibitor of mitochondrial transporters for basic amino acids and phylogenetically related …