Recent advances in biocatalysis with chemical modification and expanded amino acid alphabet
The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …
have found widespread applications in improving the intrinsic activities of proteins. Although …
Recent advances in ω-transaminase-mediated biocatalysis for the enantioselective synthesis of chiral amines
Chiral amines are important components of 40–45% of small molecule pharmaceuticals and
many other industrially important fine chemicals and agrochemicals. Recent advances in …
many other industrially important fine chemicals and agrochemicals. Recent advances in …
Oxidoreductase-catalyzed synthesis of chiral amines
Chiral amines are valuable constituents of many important pharmaceutical compounds and
their intermediates. It is estimated that∼ 40%–45% of small molecule pharmaceuticals …
their intermediates. It is estimated that∼ 40%–45% of small molecule pharmaceuticals …
Effective immobilization of Bacillus subtilis in chitosan-sodium alginate composite carrier for ammonia removal from anaerobically digested swine wastewater
J Guo, C Chen, W Chen, J Jiang, B Chen, F Zheng - Chemosphere, 2021 - Elsevier
To overcome the easy loss of microorganism, the mass production of sludge and the
consumption of aeration energy during biological treatment of anaerobically digested swine …
consumption of aeration energy during biological treatment of anaerobically digested swine …
Pseudomonas putida KT2440 is HV1 certified, not GRAS
LFC Kampers, RJM Volkers… - Microbial …, 2019 - Wiley Online Library
Pseudomonas putida is rapidly becoming a workhorse for industrial production due to its
metabolic versatility, genetic accessibility and stress‐resistance properties. The P. putida …
metabolic versatility, genetic accessibility and stress‐resistance properties. The P. putida …
Deracemization of Racemic Amines to Enantiopure (R)‐ and (S)‐amines by Biocatalytic Cascade Employing ω‐Transaminase and Amine Dehydrogenase
A one‐pot deracemization strategy for α‐chiral amines is reported involving an
enantioselective deamination to the corresponding ketone followed by a stereoselective …
enantioselective deamination to the corresponding ketone followed by a stereoselective …
Enzymatic synthesis of sitagliptin intermediate using a novel ω-transaminase
GH Kim, H Jeon, TP Khobragade, MD Patil… - Enzyme and microbial …, 2019 - Elsevier
Enantiopure β-amino acids are essential precursors of various pharmaceuticals,
agrochemicals and other industrially important chemicals. In this study, we selected sixteen …
agrochemicals and other industrially important chemicals. In this study, we selected sixteen …
Cross-linked β-mannanase aggregates: preparation, characterization, and application for producing partially hydrolyzed guar gum
S Behera, MJ Dev, RS Singhal - Applied Biochemistry and Biotechnology, 2022 - Springer
Abstract β-Mannanase capable of hydrolyzing β-1, 4-linkages in guar gum was immobilized
as cross-linked enzyme aggregates (M-CLEAs). The aggregation and cross-linking process …
as cross-linked enzyme aggregates (M-CLEAs). The aggregation and cross-linking process …
Parallel anti-sense two-step cascade for alcohol amination leading to ω-amino fatty acids and α, ω-diamines
Running two two-step cascades in parallel anti-sense to transform an alcohol to an amine
allowed the conversion of ω-hydroxy fatty acids (ω-HFAs) and α, ω-diols to the …
allowed the conversion of ω-hydroxy fatty acids (ω-HFAs) and α, ω-diols to the …
[HTML][HTML] Metabolic engineering of Pseudomonas putida KT2440 for medium-chain-length fatty alcohol and ester production from fatty acids
Medium-chain-length fatty alcohols have broad applications in the surfactant, lubricant, and
cosmetic industries. Their acetate esters are widely used as flavoring and fragrance …
cosmetic industries. Their acetate esters are widely used as flavoring and fragrance …