Trimetazidine therapy in coronary artery disease: the impact on oxidative stress, inflammation, endothelial dysfunction, and long-term prognosis
Background: In coronary artery disease (CAD), reduction of perfusion in coronary arteries is
followed by increases of oxidative stress and decreases of adenosine triphosphate reserve …
followed by increases of oxidative stress and decreases of adenosine triphosphate reserve …
[PDF][PDF] Thrombosis, an important piece in the COVID-19 puzzle: From pathophysiology to therapy
E Bobescu, LG Marceanu, A Covaciu… - Anatolian Journal of …, 2021 - jag.journalagent.com
ABSTRACT A lot of data about coronavirus disease 2019 (COVID-19) have been already
published; however, these still form only a part of the pandemic puzzle. Once we have all the …
published; however, these still form only a part of the pandemic puzzle. Once we have all the …
Association between insulin resistance and aspirin or clopidogrel resistance in Chinese patients with recent ischemic stroke/TIA
W Jia, Q Jia, Y Zhang, X Zhao, Y Wang - Neurological Research, 2021 - Taylor & Francis
Objective: This study aims to discover whether insulin resistance is an independent predictor
for antiplatelet drug resistance in patients with ischemic cerebrovascular disease. Methods …
for antiplatelet drug resistance in patients with ischemic cerebrovascular disease. Methods …
[HTML][HTML] The Influence of Non-High-Density Lipoprotein Cholesterol on the Efficacy of Genotype-Guided Dual Antiplatelet Therapy in Preventing Stroke Recurrence
Q Xu, X Meng, H Li, X Xie, J Jing, J Lin, Y Jiang… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background and Purpose Non-high-density lipoprotein cholesterol (non-HDL-C), which
represents the total cholesterol content of all pro-atherogenic lipoproteins, has recently been …
represents the total cholesterol content of all pro-atherogenic lipoproteins, has recently been …
[HTML][HTML] Simultaneous determination of clopidogrel, 2-oxo-clopidogrel, and the thiol metabolite of clopidogrel in human plasma by LC-MS/MS
L Xu, R Li, J Li, Z Dong, J Zong, C Tan… - Journal of Biomedical …, 2022 - ncbi.nlm.nih.gov
Clopidogrel is a pro-drug which needs two-step metabolism to produce the active thiol
metabolite. This study aimed to explore an efficient method to simultaneously determine the …
metabolite. This study aimed to explore an efficient method to simultaneously determine the …
CYP2C19 Polymorphism in Ischemic Heart Disease Patients Taking Clopidogrel After Percutaneous Coronary Intervention in Egypt
Abstract Background Cardiovascular diseases (CVDs) are considered a leading cause of
death worldwide. Allelic variation in the CYP2C19 gene leads to a dysfunctional enzyme …
death worldwide. Allelic variation in the CYP2C19 gene leads to a dysfunctional enzyme …
Clopidogrel resistance in patients with stroke recurrence under single or dual antiplatelet treatment
Background: The factors associated with clopidogrel resistance in patients with stroke
recurrence receiving single or dual antiplatelet treatment (SAPT or DAPT) may differ. This …
recurrence receiving single or dual antiplatelet treatment (SAPT or DAPT) may differ. This …
The association between abcb1 gene polymorphism and clopidogrel response variability in stroke ischemic: a cross sectional study
R Hidayat, RA Nabilah, M Fisher, T Aninditha… - BMC neurology, 2024 - Springer
Background Clopidogrel has been the primary choice of antiplatelet in ischemic stroke that
inhibits adenosine diphosphate (ADP)-induced platelet aggregation. P-glycoprotein (P-gp) …
inhibits adenosine diphosphate (ADP)-induced platelet aggregation. P-glycoprotein (P-gp) …
Effect of prediabetes on asprin or clopidogrel resistance in patients with recent ischemic stroke/TIA
W Jia, Q Jia, Y Zhang, X Zhao, Y Wang - Neurological Sciences, 2021 - Springer
Objective Diabetes mellitus (DM) had been discovered as an independent risk factor for high
on-treatment platelet reactivity (HPR) in patients with ischemic stroke. However, studies on …
on-treatment platelet reactivity (HPR) in patients with ischemic stroke. However, studies on …
CYP2C19 polymorphisms and lipoproteins associated with clopidogrel resistance in children with Kawasaki disease in China: A prospective study
M Zhang, L Meng, Y Chen, X Li, L Shi - Frontiers in Cardiovascular …, 2022 - frontiersin.org
Background CYP2C19 genetic variation and clinical factors have been proved to be related
with clopidogrel resistance (CR) in adults, while the presence of CR in children with …
with clopidogrel resistance (CR) in adults, while the presence of CR in children with …