Obesity and colorectal cancer (CRC) are among the leading diseases causing deaths in the
world, showing a complex multifactorial pathology. Obesity is considered a risk factor in …

This narrative review aims to pinpoint mental and behavioral effects of starvation, which may
be triggered by hypoleptinemia and as such may be amenable to treatment with leptin …

Obesity is a pandemic condition of complex etiology, resulting from the increasing exposition
to obesogenic environmental factors combined with genetic susceptibility. In the past two …

Patients with monogenic obesity display numerous medical features on top of hyperphagic
obesity, but no study to date has provided an exhaustive description of their semiology. Two …

Context Homozygous leptin (LEP) and leptin receptor (LEPR) variants lead to childhood-
onset obesity. Objective To present new cases with LEP and LEPR deficiency, report the …

Breast milk is the optimal food for infants and toddlers, providing basic nutrients. It is also a
source of many biologically active substances. Among them are hormones responsible for …

Background Obesity, one of the most common chronic health conditions worldwide, is a
multifactorial disease caused by complex genetic and environmental interactions. Several …

Perinatal leptin deficiency and reduced intake of mother's milk may contribute to the
development of childhood obesity. Preterm infants have reduced leptin production, and they …

Background The effect of obesity status on bone mineral density (BMD) in adolescents and
whether there is a saturation effect is still insufficient. A cross-sectional study of adolescents …

Two psychiatric interviews of a 39-year old female with congenital leptin deficiency were
conducted to define psychological changes 14 and 165 days after initiation of treatment with …