Novel Methods to Assess Tumor Burden and Minimal Residual Disease in Genitourinary Cancers

PC Barata, KK Zarrabi, A Bex, P Grivas, K Hermann… - European urology, 2024 - Elsevier
Background and objective Advances in molecular diagnostics have ushered in a new era for
patients with prostate, renal, and urothelial cancers, with novel radiographic and molecular …

Patterned microarrays or nanoscale assemblies for optical sensing of biomarkers

X Lu, Z Li - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Array-based micro-or nanoscale substrates are particularly attractive for biomolecular
sensing due to the periodicity of the engineered nanostructures that provide impressively …

Role of UFMylation in tumorigenesis and cancer immunotherapy

L Ding, X Jiang, T Li, S Wang - Frontiers in Immunology, 2024 - frontiersin.org
Protein post-translational modifications (PTMs) represent a crucial aspect of cellular
regulation, occurring after protein synthesis from mRNA. These modifications, which include …

Unlocking Precision Medicine: Liquid Biopsy Advancements in Renal Cancer Detection and Monitoring

F Crocetto, A Falcone, BF Mirto, E Sicignano… - International Journal of …, 2024 - mdpi.com
Renal cell carcinoma (RCC) remains a formidable diagnostic challenge, especially in the
context of small renal masses. The quest for non-invasive screening tools and biomarkers …

[HTML][HTML] Effective strategies to enhance the diagnosis and treatment of RCC: the application of biocompatible materials

J Li, P Luo, S Liu, M Fu, A Lin, Y Liu, Z He, K Qiao… - Materials Today Bio, 2024 - Elsevier
Renal cell carcinoma (RCC) is recognized as one of the three primary malignant tumors
affecting the urinary system, posing a significant risk to human health and life. Despite …

Non-coding transcriptome profiles in clear-cell renal cell carcinoma

T Tesarova, O Fiala, M Hora, R Vaclavikova - Nature Reviews Urology, 2024 - nature.com
Clear-cell renal cell carcinoma (ccRCC) is a common urological malignancy with an
increasing incidence. The development of molecular biomarkers that can predict the …

Circulating microRNA-155-3p levels predicts response to first line immunotherapy in patients with metastatic renal cell carcinoma

M Soleimani, M Thi, S Janfaza, G Ozcan, S Mazurek… - Scientific Reports, 2024 - nature.com
Predictive biomarkers of response to immune checkpoint-based therapies (ICI) remain a
critically unmet need in the management of advanced renal cell carcinoma (RCC). The …

Galectin-1 蛋白在肾透明细胞癌组织中的表达及患者预后判断中的价值

常晨, 毕新刚, 常乐 - 临床泌尿外科杂志, 2024 - whuhzzs.com
目的探讨肾透明细胞癌中半乳糖凝集素-1 (Galectin-1) 蛋白的表达变化, 并评估其在患者预后
判断方面的潜在价值. 方法采用组织微阵列和免疫组织化学技术对173 例肾透明细胞癌组织及其 …

DNA nanotechnology for cell-free DNA marker for tumor detection: a comprehensive overview

SS Soliman, FE Abd El-Samie… - … Nucleotides & Nucleic …, 2024 - Taylor & Francis
Advancements in DNA nanotechnology have led to new exciting ways to detect cell-free
tumor biomarkers, revolutionizing cancer diagnostics. This article comprehensively reviews …

693P Plasma exosome microRNA-155-3p expression in patients with metastatic renal cell carcinoma treated with immune checkpoint inhibitors: Potential biomarker of …

M Soleimani, M Thi, N Saxena, DJ Khalaf… - Annals of …, 2021 - annalsofoncology.org
Background There are multiple first-line treatment options in the management of metastatic
renal cell carcinoma (mRCC). In the face of this broad treatment landscape, a reliable …