Pharmacophore and QSAR modeling of some structurally diverse azaaurones derivatives as anti-malarial activity
MC Sharma, S Sharma, P Sharma, A Kumar - Medicinal Chemistry …, 2014 - Springer
Quantitative structure–activity relationship (QSAR) and Pharmacophore studies were
performed on a series of 35 azaaurones derivatives to find out the structural requirements of …
performed on a series of 35 azaaurones derivatives to find out the structural requirements of …
Comparative QSAR and pharmacophore modeling of substituted 2-[2′-(dimethylamino) ethyl]-1, 2-dihydro-3H-dibenz[de,h]isoquinoline-1,3-diones derivatives as …
MC Sharma, S Sharma, P Sharma, A Kumar - Medicinal Chemistry …, 2013 - Springer
To elucidate the structural properties required for anti-tumor activity, four different molecular
modeling techniques; two-dimensional (2D-QSAR), group-based QSAR (G-QSAR), 3D …
modeling techniques; two-dimensional (2D-QSAR), group-based QSAR (G-QSAR), 3D …
Comprehensive structure–activity relationship analysis of substituted 5-(biphenyl-4-ylmethyl) pyrazoles derivatives as AT1 selective angiotensin II receptor …
MC Sharma, DV Kohli - Medicinal Chemistry Research, 2013 - Springer
Two-and three-dimensional quantitative structure activity relationship studies of 5-(biphenyl-
4-ylmethyl) pyrazoles derivatives were performed for their AT 1 selective angiotensin II …
4-ylmethyl) pyrazoles derivatives were performed for their AT 1 selective angiotensin II …
Structural insights for substituted acyl sulfonamides and acyl sulfamides derivatives of imidazole as angiotensin II receptor antagonists using molecular modeling …
MC Sharma, S Sharma, P Sharma, A Kumar… - Journal of the Taiwan …, 2014 - Elsevier
Molecular modeling studies were carried out on a series of substituted acyl sulfonamides
and acyl sulfamides derivatives of imidazole as angiotensin II AT 1 receptor antagonists in …
and acyl sulfamides derivatives of imidazole as angiotensin II AT 1 receptor antagonists in …
QSAR and pharmacophore approach on substituted imidazole derivatives as angiotensin II receptor antagonists
MC Sharma, S Sharma, P Sharma, A Kumar… - Medicinal Chemistry …, 2014 - Springer
A QSAR analyses of 32 aminomethyl and acylaminomethyl substituents derivatives were
carried out to interpret the relationship between structural properties and angiotensin II AT 1 …
carried out to interpret the relationship between structural properties and angiotensin II AT 1 …
Molecular modeling and pharmacophore approach for structural requirements of some 2-substituted-1-naphthols derivatives as potent 5-lipoxygenase inhibitors
MC Sharma, S Sharma, P Sharma, A Kumar - Medicinal Chemistry …, 2013 - Springer
Molecular modeling and pharmacophore study has been performed on a series of 2-
Substituted-1-naphthols derivatives with potent 5-lipoxygenase inhibitory activity. Structural …
Substituted-1-naphthols derivatives with potent 5-lipoxygenase inhibitory activity. Structural …
Molecular modeling studies of substituted 3, 4-dihydroxychalcone derivatives as 5-lipoxygenase and cyclooxygenase inhibitors
MC Sharma - Medicinal Chemistry Research, 2014 - Springer
A fifty-four compound series of 5-lipoxygenase and cyclooxygenase inhibitory activity of
substituted 3, 4-dihydroxychalcones was subjected to the development of a robust …
substituted 3, 4-dihydroxychalcones was subjected to the development of a robust …
Comprehensive two and three-dimensional QSAR studies of 3-substituted 6-butyl-1, 2dihydropyridin-2-ones derivatives as angiotensin II receptor antagonists
MC Sharma, DV Kohli - Medicinal Chemistry Research, 2013 - Springer
In this paper, an attempt was made to develop a two and three-dimensional QSAR models
on a series of 3-substituted 6-butyl-1, 2 dihydropyridin-2-ones derivatives acting as …
on a series of 3-substituted 6-butyl-1, 2 dihydropyridin-2-ones derivatives acting as …
[HTML][HTML] Structural requirements of N-aryl-oxazolidinone-5-carboxamide derivatives for anti-HIV protease activity using molecular modelling techniques
MC Sharma - Journal of Taibah University for Science, 2014 - Elsevier
Two-and three-dimensional quantitative structure–activity relation (QSAR) models were
generated for a series of N-aryl-oxazolidinone-5-carboxamide derivatives to identify potent …
generated for a series of N-aryl-oxazolidinone-5-carboxamide derivatives to identify potent …
Comparative QSAR and pharmacophore analysis for a series of 2,4-dihydro-3H-1,2,4-triazol-3-ones derivatives as angiotensin II AT1 receptor antagonists
MC Sharma, S Sharma, P Sharma, A Kumar… - Medicinal Chemistry …, 2014 - Springer
This article describes the development of a robust two-dimensional (2D), Group-based
quantitative structure–activity relationship (G-QSAR), k-nearest neighbor (kNN), and …
quantitative structure–activity relationship (G-QSAR), k-nearest neighbor (kNN), and …