Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems

S Sifakis, VP Androutsopoulos, AM Tsatsakis… - Environmental …, 2017 - Elsevier
Endocrine disrupting chemicals (EDCs) comprise a group of chemical compounds that have
been examined extensively due to the potential harmful effects in the health of human …

Metabolism and metabolites of polychlorinated biphenyls

FA Grimm, D Hu, I Kania-Korwel… - Critical reviews in …, 2015 - Taylor & Francis
The metabolism of polychlorinated biphenyls (PCBs) is complex and has an impact on
toxicity, and thereby on the assessment of PCB risks. A large number of reactive and stable …

Exposure to 6-PPD quinone at environmentally relevant concentrations causes abnormal locomotion behaviors and neurodegeneration in Caenorhabditis elegans

X Hua, X Feng, G Liang, J Chao… - Environmental Science & …, 2023 - ACS Publications
6-PPD quinone (6-PPDQ) can be transformed from 6-PPD through ozonation. Nevertheless,
the potential neurotoxicity of 6-PPDQ after long-term exposure and the underlying …

[HTML][HTML] Evaluation of the binding performance of flavonoids to estrogen receptor alpha by Autodock, Autodock Vina and Surflex-Dock

Q Xue, X Liu, P Russell, J Li, W Pan, J Fu… - … and Environmental Safety, 2022 - Elsevier
Molecular docking is a widely used method to predict the binding modes of small-molecule
ligands to the target binding site. However, it remains a challenge to identify the correct …

Risk for animal and human health related to the presence of dioxins and dioxin‐like PCBs in feed and food

EFSA Panel on Contaminants in the Food Chain … - Efsa …, 2018 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific opinion on the risks for
animal and human health related to the presence of dioxins (PCDD/Fs) and DL‐PCBs in …

Thyroid-disrupting chemicals and brain development: an update

BB Mughal, JB Fini, BA Demeneix - Endocrine connections, 2018 - ec.bioscientifica.com
This review covers recent findings on the main categories of thyroid hormone–disrupting
chemicals and their effects on brain development. We draw mostly on epidemiological and …

Reproductive toxicity of combined effects of endocrine disruptors on human reproduction

S Dutta, P Sengupta, S Bagchi, BS Chhikara… - Frontiers in Cell and …, 2023 - frontiersin.org
Confluence of environmental, genetic, and lifestyle variables is responsible for deterioration
of human fecundity. Endocrine disruptors or endocrine disrupting chemicals (EDCs) may be …

Comparative analyses of the 12 most abundant PCB congeners detected in human maternal serum for activity at the thyroid hormone receptor and ryanodine receptor

S Sethi, RK Morgan, W Feng, Y Lin, X Li… - … science & technology, 2019 - ACS Publications
Polychlorinated biphenyls (PCBs) pose significant risk to the developing human brain;
however, mechanisms of PCB developmental neurotoxicity (DNT) remain controversial. Two …

Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs)

K Dhakal, GS Gadupudi, HJ Lehmler… - … Science and Pollution …, 2018 - Springer
Polychlorinated biphenyls (PCBs), a group of 209 congeners that differ in the number and
position of chlorines on the biphenyl ring, are anthropogenic chemicals that belong to the …

Assessing indoor dust interference with human nuclear hormone receptors in cell-based luciferase reporter assays

AS Young, T Zoeller, R Hauser… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: Per-and polyfluoroalkyl substances (PFAS), organophosphate esters (OPEs),
and polybrominated diphenyl ethers (PBDEs) are hormone-disrupting chemicals that …