[HTML][HTML] Dynamics in liver stiffness measurements predict outcomes in advanced chronic liver disease

G Semmler, Z Yang, L Fritz, F Köck, BS Hofer, L Balcar… - Gastroenterology, 2023 - Elsevier
Background & Aims Liver stiffness measurements (LSMs) provide an opportunity to monitor
liver disease progression and regression noninvasively. We aimed to determine the …

Hepatic immune regulation and sex disparities

P Burra, A Zanetto, B Schnabl, T Reiberger… - Nature Reviews …, 2024 - nature.com
Chronic liver disease is a major cause of morbidity and mortality worldwide. Epidemiology,
clinical phenotype and response to therapies for gastrointestinal and liver diseases are …

Incomplete response to ursodeoxycholic acid in primary biliary cholangitis: criteria, epidemiology, and possible mechanisms

LX Huang, ZL Wang, R Jin, HS Chen… - Expert Review of …, 2022 - Taylor & Francis
Introduction As a common autoimmune disease with the characteristic of early complication,
primary biliary cholangitis (PBC) leads to an increasing number of mortalities among people …

Etiological cure prevents further decompensation and mortality in patients with cirrhosis with ascites as the single first decompensating event

M Tonon, L Balcar, G Semmler, V Calvino… - Hepatology, 2023 - journals.lww.com
Etiological cure prevents further decompensation and mortali... : Hepatology Etiological cure
prevents further decompensation and mortality in patients with cirrhosis with ascites as the single …

Evaluation of potential hepatic recompensation criteria in patients with PBC and decompensated cirrhosis

BS Hofer, L Burghart, E Halilbasic… - Alimentary …, 2024 - Wiley Online Library
Background Aetiological therapy improves liver function and may enable hepatic
recompensation in decompensated cirrhosis. Aims We explored the potential for …

Longitudinal outcomes of obeticholic acid therapy in ursodiol‐nonresponsive primary biliary cholangitis: stratifying the impact of add‐on fibrates in real‐world practice

E Gómez, JL Montero, E Molina… - Alimentary …, 2024 - Wiley Online Library
Background Suboptimal response to ursodeoxycholic acid occurs in 40% of primary biliary
cholangitis (PBC) patients, affecting survival. Achieving a deep response (normalisation of …

CT and MR imaging of primary biliary cholangitis: a pictorial review

Y Zhang, T Zheng, Z Huang, B Song - Insights into Imaging, 2023 - Springer
Primary biliary cholangitis (PBC) is a rare chronic autoimmune-mediated cholestatic liver
disease involving medium and small bile ducts that can lead to liver fibrosis and cirrhosis. To …

[HTML][HTML] Spleen stiffness measurement across the spectrum of liver disease patients in real-world practice

MA Lantinga, LA van Kleef, CM den Hoed… - Journal of Clinical and …, 2023 - Elsevier
Objectives Spleen stiffness measurement (SSM) provides a non-invasive surrogate marker
for clinical significant portal hypertension (CSPH). Results obtained in highly selected …

Non-invasive assessment of esophageal and fundic varices in patients with primary biliary cholangitis

Y Zhang, C Huang, F Meng, X Hu, X Huang… - European …, 2024 - Springer
Abstract Objectives The Baveno VII consensus recommends endoscopic screening for
varicose veins in cases of liver stiffness measurement (LSM)≥ 20 kPa or platelet count≤ …

Ultrasound imaging findings in primary biliary cholangitis

Y Zhang, X Hu, J Chang, W Li, C Huang, H Zhang… - BMC …, 2023 - Springer
Background Our study aimed to analyze the characteristics of ultrasound images
corresponding to each histological stage of primary biliary cholangitis (PBC). Methods We …