Hepatocytes, the major parenchymal cells in the liver, play pivotal roles in metabolism,
detoxification, and protein synthesis. Hepatocytes also activate innate immunity against …

Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …

Background The measurement of circulating substrate concentrations does not provide
information about substrate kinetics. It, therefore, remains unclear if a decrease in plasma …

Inflammation and the coagulation cascade are considered to be the potential mechanisms of
ambient particulate matter (PM) exposure-induced adverse cardiovascular events. Tumor …

Over the last two decades, it became evident that factor XIII (FXIII) is not only a crucial
determinant of clot characteristics but also has potentially important functions in many …

Autologous platelet-rich plasma (PRP) preparations are prepared at the point of care.
Centrifugation cellular density separation sequesters a fresh unit of blood into three main …

Trauma patients present to the emergency department with a spectrum of fibrinolytic activity.
This wide variance in fibrinolysis activity is a complex multifactorial process impacted by the …

Background Exosomes are cell-derived circulating vesicles that play an important role in cell–
cell communication. Exosomes are actively assembled and carry messenger RNAs …

Background There is evidence indicating that both lipoprotein (a)[Lp (a)] and fibrinogen (FIB)
are associated with mortality, However, the impact of their combination on mortality has not …

Purpose: The coronavirus disease (COVID-19) pandemic poses a global threat, and
identification of its prognostic biomarkers could prove invaluable. Fibrinogen (FIB) could be …