Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin

R Ginwala, R Bhavsar, DGI Chigbu, P Jain, ZK Khan - Antioxidants, 2019 - mdpi.com
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …

Anti-inflammatory effects of flavonoids in neurodegenerative disorders

C Spagnuolo, S Moccia, GL Russo - European journal of medicinal …, 2018 - Elsevier
Neuroinflammation is one of the main mechanisms involved in the progression of several
neurodegenerative diseases, such as Parkinson, Alzheimer, multiple sclerosis, amyotrophic …

The role of flavonoids in autoimmune diseases: Therapeutic updates

KRR Rengasamy, H Khan, S Gowrishankar… - Pharmacology & …, 2019 - Elsevier
Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

The roles of flavonols/flavonoids in neurodegeneration and neuroinflammation

Z Calis, R Mogulkoc, AK Baltaci - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
The inflammatory process in the human body is a physiological response involving many
cellular types and mediators. It results in scar formation to separate the damaged area from …

Recent advances in extracting phenolic compounds from food and their use in disease prevention and as cosmetics

R Dias, H Oliveira, I Fernandes… - Critical Reviews in …, 2021 - Taylor & Francis
Phenolic compounds in plants are essential components of human nutrition, which provide
various health benefits. However, some missing links became the research in phenolic …

Antioxidants in plants: A valorization potential emphasizing the need for the conservation of plant biodiversity in Cuba

G Llauradó Maury, D Méndez Rodríguez, S Hendrix… - Antioxidants, 2020 - mdpi.com
Plants are phytochemical hubs containing antioxidants, essential for normal plant
functioning and adaptation to environmental cues and delivering beneficial properties for …

Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: a comprehensive review

M Sohel, S Aktar, P Biswas, MA Amin… - Cancer …, 2023 - Wiley Online Library
Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …

Bioactivity and Bioavailability of the Major Metabolites of Crocus sativus L. Flower

N Moratalla-López, MJ Bagur, C Lorenzo… - Molecules, 2019 - mdpi.com
Crocus sativus L. has been cultivated throughout history to obtain its flowers, whose dried
stigmas give rise to the spice known as saffron. Crocetin esters, picrocrocin, and safranal are …

Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis

D Michaličková, T Hrnčíř, NK Canová… - European journal of …, 2020 - Elsevier
Multiple sclerosis (MS) is a neurologic autoimmune disorder featured by chronic
inflammation of the central nervous system, demyelination and axonal damage. Recently …

Apigenin: A current review on its beneficial biological activities

X Zhou, F Wang, R Zhou, X Song… - Journal of Food …, 2017 - Wiley Online Library
Abstract Apigenin, identified as 4′, 5, 7‐trihydroxyflavone, is a natural flavonoid compound
present in a variety of fruits, vegetables, functional foods, and medicinal plants. Many studies …