In the past decade, hyperpolarized (HP) contrast agents have been under active
development for MRI applications to address the twin challenges of functional and …

Accurate diagnosis is crucial to improve the treatment and prognosis of respiratory disease,
especially lung cancer. Tumors and lesions located deep in the lung are directly accessible …

Objectives To visualize and quantitatively assess regional lung function of survivors of
COVID-19 who were hospitalized using pulmonary free-breathing 1H MRI. Methods A total …

Purpose 129Xe MRI and MRS signals from airspaces, membrane tissues (M), and red blood
cells (RBCs) provide measurements of pulmonary gas exchange. However, 129Xe …

Objective To comprehensively assess the impact of aging, cigarette smoking, and chronic
obstructive pulmonary disease (COPD) on pulmonary physiology using 129 Xe MR …

Purpose To demonstrate the feasibility of compressed sensing (CS) to accelerate the
acquisition of hyperpolarized (HP) 129Xe multi‐b diffusion MRI for quantitative assessments …

Background Lung compliance, a biomarker of pulmonary fibrosis, is generally measured
globally. Hyperpolarized 129Xe gas MRI offers the potential to evaluate lung compliance …

Pulmonary diseases usually result in changes of the blood‐gas exchange function in the
early stages. Gas exchange across the respiratory membrane and gas diffusion in the …

We report a dual-signal chemical exchange saturation transfer (Dusi-CEST) strategy for drug
delivery and detection in living cells. The two signals can be detected by operators in …

Purpose To map physiological gas exchange parameters using dissolved hyperpolarized
(HP) 129Xe in a rat model of regional radiation‐induced lung injury (RILI) with spiral‐IDEAL …