The musculoskeletal system evolved in mammals to perform diverse functions that include
locomotion, facilitating breathing, protecting internal organs, and coordinating global energy …

There are both theoretical and empirical underpinnings that provide evidence that the
musculoskeletal system develops, functions, and ages as a whole. Thus, the risk of …

Physical exercise is able to improve skeletal health. However, the mechanisms are poorly
known. Irisin, a novel exercise-induced myokine, secreted by skeletal muscle in response to …

Objectives Estimating body mass from skeletal dimensions is widely practiced, but methods
for estimating its components (lean and fat mass) are poorly developed. The ability to …

Clinical evidence indicates a close association between muscle dysfunction and bone loss;
however, the underlying mechanisms remain unclear. Here, we report that muscle …

The musculoskeletal conditions osteoporosis and sarcopenia are highly prevalent in older
adults. Osteoporosis is characterized by low bone mass and microarchitectural deterioration …

The prescription of an effective therapeutic exercise program requires the right dosage of the
right exercise, at the right time for that patient. The therapist must understand and apply …

The biological age (BA) equation is a prediction model that utilizes an algorithm to combine
various biological markers of ageing. Different from traditional concepts, the BA equation …

Body mass prediction from the skeleton most commonly employs femoral head diameter
(FHD). However, theoretical predictions and empirical data suggest the relationship …

Background Osteosarcopenia is a common condition characterized by the loss of both bone
and muscle mass, which can lead to an increased risk of fractures and disability in older …