Oxidative stress, inflammation and colorectal cancer: an overview

A Bardelčíková, J Šoltys, J Mojžiš - Antioxidants, 2023 - mdpi.com
Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

The importance of antioxidant activity for the health-promoting effect of lycopene

A Kulawik, J Cielecka-Piontek, P Zalewski - Nutrients, 2023 - mdpi.com
Lycopene is a compound of colored origin that shows strong antioxidant activity. The
positive effect of lycopene is the result of its pleiotropic effect. The ability to neutralize free …

Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohn's disease: a multi-omics Mendelian randomization study

S Xu, X Li, S Zhang, C Qi, Z Zhang, R Ma, L Xiang… - BMC medicine, 2023 - Springer
Background Oxidative stress (OS) is a key pathophysiological mechanism in Crohn's
disease (CD). OS-related genes can be affected by environmental factors, intestinal …

Oxidative stress in the pathogenesis of Crohn's disease and the interconnection with immunological response, microbiota, external environmental factors, and …

E Alemany-Cosme, E Sáez-González, I Moret… - Antioxidants, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a complex multifactorial disorder in which external and
environmental factors have a large influence on its onset and development, especially in …

Antioxidants as protection against reactive oxidative stress in inflammatory bowel disease

S Jarmakiewicz-Czaja, K Ferenc, R Filip - Metabolites, 2023 - mdpi.com
Inflammatory bowel disease (IBD) belongs to a group of chronic diseases characterised by
periods of exacerbation and remission. Despite many studies and observations, its …

The emerging role of oxidative stress in inflammatory bowel disease

P Muro, L Zhang, S Li, Z Zhao, T Jin, F Mao… - Frontiers in …, 2024 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic immune-mediated condition that affects the
digestive system and includes Crohn's disease (CD) and ulcerative colitis (UC). Although …

Anti‐Inflammatory, Antioxidant, and Healing‐Promoting Effects of Aloe vera Extract in the Experimental Colitis in Rats

MA Naini, A Zargari-Samadnejad… - Evidence‐Based …, 2021 - Wiley Online Library
Background. Ulcerative colitis is a worldwide chronic gastrointestinal disease characterized
by variable extensions of colon mucosal inflammation. The available drugs have an …

Natural coumarin derivatives activating Nrf2 signaling pathway as lead compounds for the design and synthesis of intestinal anti-inflammatory drugs

LC Di Stasi - Pharmaceuticals, 2023 - mdpi.com
Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor related to stress
response and cellular homeostasis that plays a key role in maintaining the redox system …

Protective effect of tuna bioactive peptide on dextran sulfate sodium-induced colitis in mice

XW Xiang, XL Zhou, R Wang, CH Shu, YF Zhou… - Marine Drugs, 2021 - mdpi.com
Bioactive peptides isolated from marine organisms have shown to have potential anti-
inflammatory effects. This study aimed to investigate the intestinal protection effect of low …

[HTML][HTML] Oligosaccharides of Polygonatum Cyrtonema Hua ameliorates dextran sulfate sodium-induced colitis and regulates the gut microbiota

J Xu, C Tang, AU Din, Y Lu, X Ma, T Zhang, J Wu… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) is one common chronic inflammatory bowel disease that causes
severe side effects, and expensive treatment limits effective and sustained treatment of UC …