Synthesis of antimicrobial benzimidazole–pyrazole compounds and their biological activities

M Marinescu - Antibiotics, 2021 - mdpi.com
The synthesis of new compounds with antimicrobial and antiviral properties is a central
objective today in the context of the COVID-19 pandemic. Benzimidazole and pyrazole …

Benzimidazole scaffolds as promising antiproliferative agents: A review

S Tahlan, S Kumar, S Kakkar, B Narasimhan - BMC chemistry, 2019 - Springer
Cancer is one of the most serious medical problem and second leading cause of death in
the world, characterized by a deregulation of the cell cycle which mainly results in a …

A panoramic review of benzimidazole derivatives and their potential biological activity

H Hernández-López… - Mini Reviews in …, 2022 - ingentaconnect.com
The therapeutic potential of the benzimidazole nucleus has been recognized since 1944,
and it is an important heterocycle system due to its presence in a wide range of bioactive …

Synthesis, density functional theory study and in vitro antimicrobial evaluation of new benzimidazole Mannich bases

M Marinescu, LO Cinteză, GI Marton, MC Chifiriuc… - BMC chemistry, 2020 - Springer
The tri-component synthesis of novel chiral benzimidazole Mannich bases, by reaction
between benzimidazole, aqueous 30% formaldehyde and an amine, the biological …

Synthesis of Benzimidazole‐Sulfonyl Derivatives and Their Biological Activities

E Mulugeta, Y Samuel - Biochemistry Research International, 2022 - Wiley Online Library
Currently, the synthesis of new compounds with potential bioactivities has become a central
issue in the drug discovery arena. Among these new compounds, benzimidazole‐sulfonyl …

Structural diversity and luminescent properties of coordination complexes obtained from trivalent lanthanide ions with the ligands: tris ((1H-benzo [d] imidazol-2-yl) …

A Cruz-Navarro, D Hernández-Romero… - Coordination Chemistry …, 2021 - Elsevier
Herein we discuss the contribution of the NTB and BBP ligands in the coordination of
trivalent lanthanide ions. There is a very versatile chemistry in these two N-donor ligands …

Synthesis and anti-cancer applications of benzimidazole derivatives-recent studies

YK Tyagi, G Jali, R Singh - Anti-Cancer Agents in Medicinal …, 2022 - benthamdirect.com
Background: Cancer is a life-threatening disease. Anti-cancer drugs are the focus of
research. The heterocyclic molecules like benzimidazole occupy a central position in …

Synthesis, characterization and single crystal X-ray studies of pincer type Ni (II)-Schiff base complexes: Application in synthesis of 2-substituted benzimidazoles

B Agrahari, S Layek, R Ganguly, N Dege… - Journal of Organometallic …, 2019 - Elsevier
Five new pincer type Ni (II)-Schiff base complexes of the general formula [NiL 1 (PPh 3)]
1,[NiL 2 (PPh 3)] 2,[NiL 3 (PPh 3)] 3,[NiL 4 (PPh 3)] 4 and [NiL 4 (4-MePy)] 5 [where H 2 L 1 …

Development of homogeneous polyamine organocatalyst for the synthesis of 2‐aryl‐substituted benzimidazole and benzoxazole derivatives

H Kottayil, S Machingal, S Parackal B… - Journal of …, 2020 - Wiley Online Library
A new polyamine was prepared by the ring opening polymerization of epichlorohydrin and
properly characterized. The catalytic property of the prepared polymer was assessed by …

Thioether-substituted Benzimidazolium Salts: Synthesis, Characterization, Crystal Structure, and Their Inhibitory Properties Against Acetylcholinesterase and Xanthine …

K Yavuz, SAA Noma, B Şen, T Taskin-Tok… - Journal of Molecular …, 2023 - Elsevier
The sulfurous compounds are known as organosulfur, which has been associated with
numerous biological activities in both natural products and synthetic organic compounds. In …