Correlation and association analyses in microbiome study integrating multiomics in health and disease

Y Xia - Progress in molecular biology and translational …, 2020 - Elsevier
Correlation and association analyses are one of the most widely used statistical methods in
research fields, including microbiome and integrative multiomics studies. Correlation and …

Tools for analysis of the microbiome

J Galloway-Peña, B Hanson - Digestive diseases and sciences, 2020 - Springer
Over the past decade, it has become exceedingly clear that the microbiome is a critical factor
in human health and disease and thus should be investigated to develop innovative …

[PDF][PDF] MicrobiomeAnalyst: a web-based tool for comprehensive statistical, visual and meta-analysis of microbiome data

A Dhariwal, J Chong, S Habib, IL King… - Nucleic acids …, 2017 - academic.oup.com
The widespread application of next-generation sequencing technologies has revolutionized
microbiome research by enabling high-throughput profiling of the genetic contents of …

Untargeted metabolomics as a diagnostic tool in NAFLD: discrimination of steatosis, steatohepatitis and cirrhosis

M Masarone, J Troisi, A Aglitti, P Torre, A Colucci… - Metabolomics, 2021 - Springer
Abstract Introduction Non-Alcoholic Fatty Liver Disease encompasses a spectrum of
diseases ranging from simple steatosis to steatohepatitis (or NASH), up to cirrhosis and …

Obesity and mortality after breast cancer by race/ethnicity: The California Breast Cancer Survivorship Consortium

ML Kwan, EM John, BJ Caan, VS Lee… - American journal of …, 2014 - academic.oup.com
We investigated body size and survival by race/ethnicity in 11,351 breast cancer patients
diagnosed from 1993 to 2007 with follow-up through 2009 by using data from …

Experimental detection of short regulatory motifs in eukaryotic proteins: tips for good practice as well as for bad

TJ Gibson, H Dinkel, K Van Roey, F Diella - Cell Communication and …, 2015 - Springer
It has become clear in outline though not yet in detail how cellular regulatory and signalling
systems are constructed. The essential machines are protein complexes that effect …

Dynamic and modularized MicroRNA regulation and its implication in human cancers

J Shu, BVRE Silva, T Gao, Z Xu, J Cui - Scientific reports, 2017 - nature.com
MicroRNA is responsible for the fine-tuning of fundamental cellular activities and human
disease development. The altered availability of microRNAs, target mRNAs, and other types …

De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation

A Dwivedy, A Ashraf, B Jha, D Kumar… - Communications …, 2021 - nature.com
Intracellular pathogens including Mycobacterium tuberculosis (Mtb) have evolved with
strategies to uptake amino acids from host cells to fulfil their metabolic requirements …

Urinary metabolomics in pediatric obesity and NAFLD identifies metabolic pathways/metabolites related to dietary habits and gut-liver axis perturbations

J Troisi, L Pierri, A Landolfi, F Marciano, A Bisogno… - Nutrients, 2017 - mdpi.com
To get insight into still elusive pathomechanisms of pediatric obesity and non-alcoholic fatty
liver disease (NAFLD) we explored the interplay among GC-MS studied urinary …

Fluxer: a web application to compute, analyze and visualize genome-scale metabolic flux networks

A Hari, D Lobo - Nucleic acids research, 2020 - academic.oup.com
Next-generation sequencing has paved the way for the reconstruction of genome-scale
metabolic networks as a powerful tool for understanding metabolic circuits in any organism …