Tissues stiffen during aging and during the pathological progression of cancer, fibrosis, and
cardiovascular disease. Extracellular matrix stiffness is emerging as a prominent mechanical …

The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …

Advanced glycation end products (AGEs), a group of compounds that are formed by non-
enzymatic reactions between carbonyl groups of reducing sugars and free amino groups of …

Obesity is an emerging pandemic driven by consumption of a diet rich in fat and highly
refined carbohydrates (a Western diet) and a sedentary lifestyle in both children and adults …

Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …

Background Advanced glycation end products (AGEs) play a crucial role in the onset,
progression, and propagation of both macroangiopathy and microangiopathy complications …

The extracellular matrix of cirrhotic liver tissue is highly crosslinked. Here we show that
advanced glycation end-products (AGEs) mediate crosslinking in liver extracellular matrix …

Receptor for advanced glycation end products (RAGE) is a 45 kDa transmembrane receptor
of immunoglobulin family that can bind to various endogenous and exogenous ligands and …

Background: Oxidative stress, which occurs as a result of an imbalance between free-radical
production and antioxidant defense mechanisms, has been implicated in the pathogenesis …

Coronary artery disease (CAD) remains one of the most important causes of morbidity and
mortality worldwide, and the availability of percutaneous or surgical revascularization …