Increasing evidence suggests estrogen and estrogen signaling pathway disturbances
across psychiatric disorders. Estrogens are not only crucial in sexual maturation and …

Estrogens and estrogen-like molecules can modify the biology of several cell types.
Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of …

During the menopausal transition, which begins four to six years before cessation of
menses, middle-aged women experience a progressive change in ovarian activity and a …

The nitric oxide (NO) signaling pathway in hypothalamic neurons plays a key role in the
regulation of the secretion of gonadotropin-releasing hormone (GnRH), which is crucial for …

The sex steroid hormones (SSHs) play several roles in regulation of various processes in
the cardiovascular, immune, muscular and neural systems. SSHs affect prenatal and …

There is perhaps no endocrine disrupting chemical more controversial than bisphenol A
(BPA). Comprising a high‐volume production chemical used in a variety of applications …

In (eco-) toxicological studies the light/dark transition (LDT) test is one of the most frequently
used behaviour assays with zebrafish eleutheroembryos. However, study results vary …

The brain undergoes extensive structural changes during adolescence, concurrent to
puberty-related physical and hormonal changes. While animal research suggests these …

Despite significant advances in understanding nephron segment patterning, many questions
remain about the underlying genes and signaling pathways that orchestrate renal progenitor …

Estrogen impacts neural development; meanwhile, it has a protective effect on the brain.
Bisphenols, primarily bisphenol A (BPA), can exert estrogen-like or estrogen-interfering …