[HTML][HTML] Sulforaphane: A broccoli bioactive phytocompound with cancer preventive potential

AE Kaiser, M Baniasadi, D Giansiracusa… - Cancers, 2021 - mdpi.com
There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Cruciferous vegetables, isothiocyanates, and bladder cancer prevention

B Abbaoui, CR Lucas, KM Riedl… - Molecular nutrition & …, 2018 - Wiley Online Library
Bladder cancer is a significant health burden due to its high prevalence, risk of mortality,
morbidity, and high cost of medical care. Epidemiologic evidence suggests that diets rich in …

Anticancer activity of sulforaphane: the epigenetic mechanisms and the Nrf2 signaling pathway

X Su, X Jiang, L Meng, X Dong… - Oxidative medicine and …, 2018 - Wiley Online Library
Sulforaphane (SFN), a compound derived from cruciferous vegetables that has been shown
to be safe and nontoxic, with minimal/no side effects, has been extensively studied due to its …

Mechanisms underlying biological effects of cruciferous glucosinolate-derived isothiocyanates/indoles: a focus on metabolic syndrome

M Esteve - Frontiers in Nutrition, 2020 - frontiersin.org
An inverse correlation between vegetable consumption and the incidence of cancer has
long been described. This protective effect is stronger when cruciferous vegetables are …

The role of isothiocyanates as cancer chemo-preventive, chemo-therapeutic and anti-melanoma agents

M Mitsiogianni, G Koutsidis, N Mavroudis, DT Trafalis… - Antioxidants, 2019 - mdpi.com
Many studies have shown evidence in support of the beneficial effects of phytochemicals in
preventing chronic diseases, including cancer. Among such phytochemicals, sulphur …

Sulforaphane as a potential remedy against cancer: Comprehensive mechanistic review

S Khan, KA Awan, MJ Iqbal - Journal of Food biochemistry, 2022 - Wiley Online Library
Sulforaphane belongs to the active class of isothiocyanates capable of delivering various
biological benefits for health promotion and disease prevention. This compound is …

Dietary isothiocyanates inhibit cancer progression by modulation of epigenome

MK Sundaram, R Preetha, S Haque, N Akhter… - Seminars in Cancer …, 2022 - Elsevier
Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …

Prenatal epigenetics diets play protective roles against environmental pollution

S Li, M Chen, Y Li, TO Tollefsbol - Clinical epigenetics, 2019 - Springer
It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …

Reviewing cancer's biology: an eclectic approach

I Diori Karidio, SH Sanlier - Journal of the Egyptian National Cancer …, 2021 - Springer
Background Cancer refers to a group of some of the worldwide most diagnosed and
deadliest pathophysiological conditions that conquered researchers' attention for decades …

Traditional uses, phytochemistry, transformation of ingredients and pharmacology of the dried seeds of Raphanus sativus L.(Raphani Semen), A comprehensive …

L Gao, H Li, B Li, H Shao, X Yu, Z Miao, L Zhang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Raphani Semen (Lai Fu-zi in Chinese, RS), the
dried seeds of Raphanus sativus L., is a traditional Chinese herbal medicine. RS has long …