Like the ancient Greek hero Hercules, striated muscle is famous for performing impressive
feats of strength. The procurement of food, breathing, and defense or escape from harm all …

The transforming growth factor-beta (TGF-β) superfamily consists of a variety of cytokines
expressed in many different cell types including skeletal muscle. Members of this …

Duchenne muscular dystrophy (DMD) is a severe and progressive muscle wasting disorder
caused by mutations in the dystrophin gene that result in the absence of the membrane …

Duchenne muscular dystrophy is the most prevalent and severe form of human muscular
dystrophy. Investigations into the molecular basis for Duchenne muscular dystrophy were …

The ex vivo effects of passive mechanical stretch on the activation of nuclear factor‐kappaB
(NF‐κB) pathways in skeletal muscles from normal and mdx mouse, a model of Duchenne …

α7β1-Integrin links laminin in the extracellular matrix with the cell cytoskeleton and therein
mediates transduction of mechanical forces into chemical signals. Muscle contraction and …

Dystroglycan is an important cell adhesion receptor linking the actin cytoskeleton, via
utrophin and dystrophin, to laminin in the extracellular matrix. To identify adhesion‐related …

Since its first description in 1990, the dystrophin–glycoprotein complex has emerged as a
critical nexus for human muscular dystrophies arising from defects in a variety of distinct …

Utrophin has been studied extensively in recent years in an effort to find a cure for
Duchenne muscular dystrophy. In this context, we previously showed that mice expressing …

MAPK signaling consists of an array of successively acting kinases. ERK1 and-2 (ERK1/2)
are major components of the greater MAPK cascade that transduce growth factor signaling …