In mammals, early adverse experiences, including mother–pup interactions, shape the
response of an individual to chronic stress or to stress-related diseases during adult life. This …

Background The lack of uniformity in the definition of treatment resistant depression (TRD)
within the Asia-Pacific (APAC) region may have implications for patient management. We …

Background Stressful life events are known as risk factors for depression, though there is
considerable heterogeneity in how people respond to stress. Previous studies have found …

Background: Treatment-resistant depression is an important contributor to the global burden
of depression. Antidepressant augmentation is a recommended treatment strategy for …

S 47445 is a positive modulator of glutamate AMPA-type receptors, possessing neurotrophic
and enhancing synaptic plasticity effects as well as pro-cognitive and anti-stress properties …

Background There are many putative mechanisms by which ketamine has its effect and
many unanswered questions about risks and benefits of long-term ketamine therapy. A …

The treatment of mood disorders, and depression, in particular, is usually complex. A large
number of factors influence both clinical presentation and treatment outcomes (Nierenberg …

In the pharmacotherapy of depressive disorders, the problem of the predictors of a
therapeutic response remains relevant, they may be important in determining treatment …

Transient global amnesia (TGA) is a benign, stress-induced neurological syndrome
associated with reversible hippocampal dysfunction that manifests as isolated …

Objetivos: Determinar la prevalencia de rasgos maladaptativos de personalidad en los
pacientes hospitalizados por depresión a través del inventario PID-5, relacionándolos con …