Systematic review of Mendelian randomization studies on risk of cancer

G Markozannes, A Kanellopoulou, O Dimopoulou… - BMC medicine, 2022 - Springer
Background We aimed to map and describe the current state of Mendelian randomization
(MR) literature on cancer risk and to identify associations supported by robust evidence …

Vitamin D and human health: evidence from Mendelian randomization studies

A Fang, Y Zhao, P Yang, X Zhang… - European Journal of …, 2024 - Springer
We summarized the current evidence on vitamin D and major health outcomes from
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …

Circulating insulin-like growth factor 1 levels and migraine risk: a Mendelian randomization study

R Abuduxukuer, PP Niu, ZN Guo, YM Xu, Y Yang - Neurology and therapy, 2022 - Springer
Introduction Preclinical studies have indicated insulin-like growth factor 1 (IGF1) as a novel
therapeutic target in the treatment of migraines. We aimed to investigate the causal effect of …

Oxidative stress linking obesity and cancer: is obesity a 'Radical trigger'to Cancer?

M Jovanović, S Kovačević, J Brkljačić… - International Journal of …, 2023 - mdpi.com
Obesity is on the rise worldwide, and consequently, obesity-related non-communicable
diseases are as well. Nutritional overload induces metabolic adaptations in an attempt to …

Childhood obesity: A potential key factor in the development of glioblastoma multiforme

P Sachdeva, S Ghosh, S Ghosh, S Han, J Banerjee… - Life, 2022 - mdpi.com
Glioblastoma multiforme (GBM) is a malignant primary tumor type of the central nervous
system (CNS). This type of brain tumor is rare and is responsible for 12–15% of all brain …

Higher circulating vitamin D levels are associated with decreased migraine risk: a Mendelian randomization study

PP Niu, X Wang, YM Xu - Frontiers in Nutrition, 2022 - frontiersin.org
Background Evidence showed the supplementation of vitamin D might have beneficial
effects for migraine patients. We aimed to investigate the causal effects of serum vitamin D …

AllergoOncology: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint EAACI‐EANO position paper

MC Turner, U Radzikowska, DE Ferastraoaru… - Allergy, 2024 - Wiley Online Library
Epidemiological studies have explored the relationship between allergic diseases and
cancer risk or prognosis in AllergoOncology. Some studies suggest an inverse association …

Role of DNA methylation in the relationship between glioma risk factors and glioma incidence: a two-step Mendelian randomization study

AE Howell, C Relton, RM Martin, J Zheng… - Scientific Reports, 2023 - nature.com
Genetic evidence suggests glioma risk is altered by leukocyte telomere length, allergic
disease (asthma, hay fever or eczema), alcohol consumption, childhood obesity, low-density …

The COX10-AS1/miR-641/E2F6 feedback loop is involved in the progression of glioma

L Liu, X Li, H Wu, Y Tang, X Li, Y Shi - Frontiers in Oncology, 2021 - frontiersin.org
Glioma is the most common primary tumour of the central nervous system and is considered
one of the greatest challenges for neurosurgery. Mounting evidence has shown that …

Alcohol intake and risk of glioma: results from three prospective cohort studies

DJ Cote, CM Samanic, TR Smith, M Wang… - European journal of …, 2021 - Springer
Purpose The association between alcohol intake and glioma remains unclear. We evaluated
the association between alcohol intake and incidence of glioma in three large, prospective …