Podosomes are a singular category of integrin-mediated adhesions important in the
processes of cell migration, matrix degradation and cancer cell invasion. Despite a wealth of …

The mechanical properties of simple entangled actin filament networks in eukaryotes are
well understood as they are predictable with model systems. The high complexity of cellular …

The aim of this thesis focuses on addressing several open questions in cell biology by using
different mathematical approaches and numerical analysis methods to study the evolution of …

Human pluripotent stem cells (hPSC) can generate almost all adult cell lineages. While it is
clear that key transcriptional programmes are important elements for maintaining …