In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

Ageing is accompanied by an inexorable loss of muscle mass and functionality and
represents a major risk factor for numerous diseases such as cancer, diabetes and …

Background Ageing is accompanied by a progressive loss of skeletal muscle mass and
strength, potentially determining the insurgence of sarcopenia. Evidence suggests that …

Background The quantity and quality of skeletal muscle are important determinants of daily
function and metabolic health. Various forms of physical exercise can improve muscle …

Age-related sarcopenia places a tremendous burden on healthcare providers and patients'
families. Blood flow restriction (BFR) training may be a promising treatment to bring …

Background N-lactoylphenylalanine (Lac-Phe) is a new form of “exerkines” closely related to
lactate (La), which may be able to inhibit appetite. Blood flow restriction (BFR) can lead to …

Objective This study explored the impact of one session of low-pressure leg blood flow
restriction (BFR) during treadmill walking on dual-task performance in older adults using the …

Blood flow restriction pressures are typically set as a percentage of the arterial occlusion
pressure. For those who do not have the ability to measure the arterial occlusion pressure …

Background: The extent to which exercise training with blood flow restriction (BFR) improves
functional performance (FP) in people with sarcopenia remains unclear. We performed a …

Abstract Background C-terminal Agrin Fragment (CAF) has emerged as a potent biomarker
for identifying sarcopenia. However, the effect of interventions on CAF concentration and the …