Cerebral small vessel disease: recent advances and future directions

HS Markus, FE de Leeuw - International Journal of Stroke, 2023 - journals.sagepub.com
Cerebral small vessel disease (SVD) causes lacunar stroke and intracerebral hemorrhage,
and is the most common pathology underlying vascular cognitive impairment. Increasingly …

Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current opinion in …, 2021 - journals.lww.com
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Vascular cognitive impairment and dementia

EC Wong, HC Chui - CONTINUUM: Lifelong Learning in …, 2022 - journals.lww.com
PURPOSE OF REVIEW This article gives a broad overview of vascular cognitive impairment
and dementia, including epidemiology, pathophysiology, clinical approach, and …

Cortical superficial siderosis is associated with reactive astrogliosis in cerebral amyloid angiopathy

CA Auger, V Perosa, SM Greenberg… - Journal of …, 2023 - Springer
Background Cortical superficial siderosis (cSS) has recently emerged as one of the most
important predictors of symptomatic intracerebral hemorrhage and is a risk factor for post …

Intracerebral haemorrhage—mechanisms, diagnosis and prospects for treatment and prevention

DJ Seiffge, S Fandler-Höfler, Y Du… - Nature Reviews …, 2024 - nature.com
Intracerebral haemorrhage (ICH) is a devastating condition associated with high mortality
and substantial residual disability among survivors. Effective treatments for the acute stages …

Prevalence, risk factors, and clinical outcomes of remote intracerebral hemorrhage after intravenous thrombolysis in acute ischemic stroke: a systematic review and …

L Qiu, F Fu, W Zhang, J He, Z Zhan, Z Cheng - Journal of neurology, 2023 - Springer
Background Hemorrhagic transformation (HT) is a common complication of alteplase
treatment. However, the prevalence rate, risk factors, and clinical outcomes of remote …

Neuropathology of vascular brain health: insights from ex vivo magnetic resonance imaging–histopathology studies in cerebral small vessel disease

SJ van Veluw, K Arfanakis, JA Schneider - Stroke, 2022 - Am Heart Assoc
Sporadic cerebral small vessel disease (SVD) is a major contributor to vascular cognitive
impairment and dementia in the aging human brain. On neuropathology, sporadic SVD is …

[HTML][HTML] Exploring cerebral amyloid angiopathy: Insights into pathogenesis, diagnosis, and treatment

M Cozza, L Amadori, V Boccardi - Journal of the Neurological Sciences, 2023 - Elsevier
Abstract Cerebral Amyloid Angiopathy (CAA) is a neurological disorder characterized by the
deposition of amyloid plaques in the walls of cerebral blood vessels. This condition poses …

[HTML][HTML] New perspectives of taxifolin in neurodegenerative diseases

R Yang, X Yang, F Zhang - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
cerebral amyloid angiopathy (CAA), and Huntington's disease (HD) are characterized by …

The Impact of Anti-Amyloid Immunotherapies on Stroke Care

PA Bilodeau, JR Dickson, MG Kozberg - Journal of Clinical Medicine, 2024 - mdpi.com
Anti-amyloid immunotherapies have recently emerged as treatments for Alzheimer's
disease. While these therapies have demonstrated efficacy in clearing amyloid-β and …