Current and novel biomarkers of thrombotic risk in COVID-19: a consensus statement from the international COVID-19 thrombosis biomarkers colloquium

DA Gorog, RF Storey, PA Gurbel, US Tantry… - Nature Reviews …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and
thromboembolic events, owing to excessive inflammation, endothelial cell activation and …

Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …

Endothelium infection and dysregulation by SARS-CoV-2: evidence and caveats in COVID-19

I Bernard, D Limonta, LK Mahal, TC Hobman - Viruses, 2020 - mdpi.com
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the acute
respiratory syndrome-coronavirus-2 (SARS-CoV-2) poses a persistent threat to global public …

Vasculopathy in COVID-19

R Flaumenhaft, K Enjyoji… - Blood, The Journal of the …, 2022 - ashpublications.org
COVID-19 is a primary respiratory illness that is frequently complicated by systemic
involvement of the vasculature. Vascular involvement leads to an array of complications …

[HTML][HTML] Autoantibodies and SARS-CoV2 infection: The spectrum from association to clinical implication: Report of the 15th Dresden Symposium on Autoantibodies

J Damoiseaux, A Dotan, MJ Fritzler, DP Bogdanos… - Autoimmunity …, 2022 - Elsevier
The relation between infections and autoimmune diseases has been extensively
investigated. Multiple studies suggest a causal relation between these two entities with …

Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality

A Philippe, R Chocron, N Gendron, O Bory, A Beauvais… - Angiogenesis, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is a respiratory disease
associated with endotheliitis and microthrombosis. Objectives To correlate endothelial …

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Q Ning, D Wu, X Wang, D Xi, T Chen, G Chen… - Signal transduction and …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

Pathophysiological mechanisms of thrombosis in acute and long COVID-19

H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

ICU admission levels of endothelial biomarkers as predictors of mortality in critically ill COVID-19 patients

AG Vassiliou, C Keskinidou, E Jahaj, P Gallos… - Cells, 2021 - mdpi.com
Endotheliopathy is suggested to be an important feature of COVID-19 in hospitalized
patients. To determine whether endotheliopathy is involved in COVID-19-associated …

Increased VWF and decreased ADAMTS-13 in COVID-19: creating a milieu for (micro) thrombosis

EJ Favaloro, BM Henry, G Lippi - Seminars in thrombosis and …, 2021 - thieme-connect.com
von Willebrand factor (VWF) is a large adhesive multimeric protein involved in hemostasis.
The larger the size (or number of VWF multimers), the greater the functionality of the protein …