Dementia is a major source of disability worldwide and there are currently no available disease-modifying treatments. Hearing loss may be associated with increased risk of …
Background Overweight and obesity are increasing worldwide. To help assess their relevance to mortality in different populations we conducted individual-participant data meta …
Depression is an accepted risk factor for dementia, but it is unclear if this relationship is causal. This study investigated whether dementia associated with depression decreases …
Context: The prevalence of frailty increases, whereas testosterone decreases, as men age. Low testosterone may be a risk factor for development of this syndrome. Objective: Our …
BB Yeap, H Alfonso, SAP Chubb… - The Journal of …, 2014 - academic.oup.com
Context: Testosterone (T) levels decline with age and lower T has been associated with increased mortality in aging men. However, the associations of its metabolites …
MC Decaroli, V Rochira - Virulence, 2017 - Taylor & Francis
Several large cohort studies have disclosed the trajectories of sex steroids changes overtime in men and their clinical significance. In men the slow, physiological decline of …
RJ Marriott, K Murray, RJ Adams, L Antonio… - Annals of internal …, 2023 - acpjournals.org
Background: Various factors modulate circulating testosterone in men, affecting interpretation of testosterone measurements. Purpose: To clarify factors associated with …
OBJECTIVES: To examine in an older population all‐cause and cause‐specific mortality associated with underweight (body mass index (BMI)< 18.5), normal weight (BMI 18.5–24.9) …
BB Yeap, Z Hyde, OP Almeida… - The Journal of …, 2009 - academic.oup.com
Context: Lower circulating testosterone concentrations are associated with metabolic syndrome, type 2 diabetes, carotid intima-media thickness, and aortic and lower limb arterial …