Radiochromic film for medical radiation dosimetry

MJ Butson, KN Peter, T Cheung, P Metcalfe - Materials Science and …, 2003 - Elsevier
Photon, electron and proton radiations are used extensively for medical purposes in
diagnostic and therapeutic procedures. Dosimetry of these radiation sources can be …

Integrating mechanism-based modeling with biomedical imaging to build practical digital twins for clinical oncology

C Wu, G Lorenzo, DA Hormuth, EABF Lima… - Biophysics …, 2022 - pubs.aip.org
Digital twins employ mathematical and computational models to virtually represent a
physical object (eg, planes and human organs), predict the behavior of the object, and …

Ten-year results of FAST: a randomized controlled trial of 5-fraction whole-breast radiotherapy for early breast cancer

AM Brunt, JS Haviland, M Sydenham… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Previous studies of hypofractionated adjuvant whole-breast radiotherapy for
early breast cancer established a 15-or 16-fraction (fr) regimen as standard. The FAST Trial …

Radiation-induced hypopituitarism after cancer therapy: who, how and when to test

KH Darzy - Nature clinical practice Endocrinology & metabolism, 2009 - nature.com
Subtle to frank abnormalities in hypothalamic–pituitary axis function are frequently seen in
cancer survivors who have received prophylactic or therapeutic cranial irradiation. The …

Correction factors to convert microdosimetry measurements in silicon to tissue in 12C ion therapy

D Bolst, S Guatelli, LT Tran, L Chartier… - Physics in Medicine …, 2017 - iopscience.iop.org
Silicon microdosimetry is a promising technology for heavy ion therapy (HIT) quality
assurance, because of its sub-mm spatial resolution and capability to determine radiation …

The Chk1 inhibitor MK-8776 increases the radiosensitivity of human triple-negative breast cancer by inhibiting autophagy

Z Zhou, Z Yang, S Wang, L Zhang, J Luo… - Acta Pharmacologica …, 2017 - nature.com
MK-8776 is a recently described inhibitor that is highly selective for checkpoint kinase 1
(Chk1), which can weaken the DNA repair capacity in cancer cells to achieve chemo …

Individual response to ionizing radiation and personalized radiotherapy

EA Domina, A Philchenkov… - Critical Reviews™ in …, 2018 - dl.begellhouse.com
Radiation therapy remains one of the most effective cancer treatments. Nevertheless,
biology-driven personalized radiation therapy that enables treatment according to the …

Hypopituitarism as a consequence of brain tumours and radiotherapy

KH Darzy, SM Shalet - Pituitary, 2005 - Springer
Radiation-induced damage to the hypothalamic-pituitary (hp) axis is associated with a wide
spectrum of subtle and frank abnormalities in anterior pituitary hormones secretion. The …

Stereotactic body radiosurgery for spinal metastatic disease: an evidence‐based review

WA Hall, LJ Stapleford, CG Hadjipanayis… - … journal of surgical …, 2011 - Wiley Online Library
Spinal metastasis is a problem that afflicts many cancer patients. Traditionally, conventional
fractionated radiation therapy and/or surgery have been the most common approaches for …

A time-resolved experimental–mathematical model for predicting the response of glioma cells to single-dose radiation therapy

J Liu, DA Hormuth, T Davis, J Yang… - Integrative …, 2021 - academic.oup.com
Purpose To develop and validate a mechanism-based, mathematical model that
characterizes 9L and C6 glioma cells' temporal response to single-dose radiation therapy in …