Macrophage membrane-encapsulated nitrogen-doped carbon quantum dot nanosystem for targeted treatment of Alzheimer's disease: Regulating metal ion …

P Ye, L Li, X Qi, M Chi, J Liu, M Xie - Journal of Colloid and Interface …, 2023 - Elsevier
The abnormal aggregation of β-amyloid protein (Aβ) is a major contributor to Alzheimer's
disease (AD). Cu 2+ homeostasis imbalance can lead to the aggregation of Aβ, resulting in …

Red Ginseng Inhibits Tau Aggregation and Promotes Tau Dissociation In Vitro

SJ Shin, YH Park, SG Jeon, S Kim… - Oxidative medicine …, 2020 - Wiley Online Library
Tau, a microtubule‐associated protein expressed in mature neurons, interacts with tubulin to
promote the assembly and stabilization of microtubules. However, abnormally …

Pseudoginsenoside-F11 attenuates cognitive dysfunction and tau phosphorylation in sporadic Alzheimer's disease rat model

L Zhu, X Hou, X Che, T Zhou, X Liu, C Wu… - Acta Pharmacologica …, 2021 - nature.com
We previously reported that pseudoginsenoside-F11 (PF11), an ocotillol-type saponin,
significantly ameliorated Alzheimer's disease (AD)-associated cognitive defects in APP/PS1 …

Catechol-Type Flavonoids from the Branches of Elaeagnus glabra f. oxyphylla Exert Antioxidant Activity and an Inhibitory Effect on Amyloid-β Aggregation

YJ Kim, E Sohn, JH Kim, MK Na, SJ Jeong - Molecules, 2020 - mdpi.com
Elaeagnus glabra f. oxyphylla (Elaeagnaceae) is a small evergreen tree with narrow
lanceolate leaves that is native to Korea. In this work, we studied the chemical composition …

What can traditional Chinese medicine do for adult neurogenesis?

W Shen, N Jiang, W Zhou - Frontiers in Neuroscience, 2023 - frontiersin.org
Adult neurogenesis plays a crucial role in cognitive function and mood regulation, while
aberrant adult neurogenesis contributes to various neurological and psychiatric diseases …

Nutrition and Aging

MH Mohajeri - International Journal of Molecular Sciences, 2023 - mdpi.com
This Special Issue focuses on the importance of nutritional interventions for the delay of age-
related conditions. Nutritional compounds have been shown to play a fundamental role in …

Acori tatarinowii rhizoma extract ameliorates Alzheimer's pathological syndromes by repairing myelin injury and lowering Tau phosphorylation in mice

Y Fu, Y Yang, J Shi, K Bishayee, L Lin… - Die Pharmazie-An …, 2020 - ingentaconnect.com
It has been shown that Acori tatarinowii rhizoma (ATR) extract can improve cognitive
functions in Alzheimer Diseas (AD) patients or animal models. In this study, we have …

A systematic screening of traditional chinese medicine identifies two novel inhibitors against the cytotoxic aggregation of amyloid beta

L Ma, J Zheng, H Chen, X Zeng, S Wang… - Frontiers in …, 2021 - frontiersin.org
The toxic aggregates of amyloid beta (Aβ) disrupt the cell membrane, induce oxidative stress
and mitochondrial dysfunction, and eventually lead to Alzheimer's disease (AD). Intervening …

JBPOS0101 regulates amyloid beta, tau, and glial cells in an Alzheimer's disease model

J Jeong, HJ Park, BR Mun, JK Jang, YM Choi… - PloS one, 2020 - journals.plos.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease characterized by
cognitive dysfunction and memory loss as the main symptoms. The deposition of amyloid …

Quantitative Analysis of 7 Compounds in Diospyros lotus Leaf Extract and Its Biological Effects on Neuroprotection and Antineuroinflammation

YJ Kim, HS Lim, JH Kim, MK Na… - Natural Product …, 2020 - journals.sagepub.com
Diospyros lotus L.(Ebenaceae) is a deciduous plant that was traditionally used to treat
various diseases such as sedation, constipation, and hypertension. However, its effects on …