Microbial communities are spatially organized in both the environment and the human body.
Although patterns exhibited by these communities are described by microbial biogeography …

Microbiomes occupy a range of niches and, in addition to having diverse compositions, they
have varied functional roles that have an impact on agriculture, environmental sciences, and …

Mismatch repair (MMR) is a conserved mechanism exploited by cells to correct DNA
replication errors both in growing cells and under nongrowing conditions. Hfq (host factor for …

One key to the success of Mycobacterium tuberculosis as a pathogen is its ability to reside in
the hostile environment of the human macrophage. Bacteria adapt to stress through a variety …

Pseudomonas aeruginosa is an opportunistic pathogen that requires iron to cause infection,
but it also must regulate the uptake of iron to avoid iron toxicity. The iron-responsive PrrF1 …

Bacteria have evolved small RNAs (sRNAs) to regulate numerous biological processes and
stress responses. While sRNAs generally are considered to be “noncoding,” a few have …

Most bacterial regulatory RNAs exert their function through base-pairing with target RNAs.
Computational prediction of targets is a busy research field that offers biologists a variety of …

Despite the expanding interest in bacterial viruses (bacteriophages), insights into the
intracellular development of bacteriophage and its impact on bacterial physiology are still …

Negative feedback is known to enable biological and man-made systems to perform reliably
in the face of uncertainties and disturbances. To date, synthetic biological feedback circuits …

Motivation The aim of this study is to assess the performance of RNA–RNA interaction
prediction tools for all domains of life. Results Minimum free energy (MFE) and alignment …