Advances in pluripotent stem cells: history, mechanisms, technologies, and applications

G Liu, BT David, M Trawczynski, RG Fessler - Stem cell reviews and …, 2020 - Springer
Over the past 20 years, and particularly in the last decade, significant developmental
milestones have driven basic, translational, and clinical advances in the field of stem cell …

Magnetic particle imaging: current and future applications, magnetic nanoparticle synthesis methods and safety measures

C Billings, M Langley, G Warrington, F Mashali… - International Journal of …, 2021 - mdpi.com
Magnetic nanoparticles (MNPs) have a wide range of applications; an area of particular
interest is magnetic particle imaging (MPI). MPI is an imaging modality that utilizes …

Micro-RNAs shuttled by extracellular vesicles secreted from mesenchymal stem cells dampen astrocyte pathological activation and support neuroprotection in in-vitro …

F Provenzano, S Nyberg, D Giunti, C Torazza, B Parodi… - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with no effective cure.
Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) …

Adipose tissue stem cells for therapy: an update on the progress of isolation, culture, storage, and clinical application

DT Chu, T Nguyen Thi Phuong, NLB Tien… - Journal of Clinical …, 2019 - mdpi.com
Adipose tissue stem cells (ASCs), known as multipotent stem cells, are most commonly used
in the clinical applications in recent years. Adipose tissues (AT) have the advantage in the …

Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis

JS Katzeff, F Bright, K Phan, JJ Kril, LM Ittner… - Brain, 2022 - academic.oup.com
Frontotemporal dementia refers to a group of neurodegenerative disorders characterized by
behaviour and language alterations and focal brain atrophy. Amyotrophic lateral sclerosis is …

[HTML][HTML] Cell therapy in ALS: An update on preclinical and clinical studies

F Sironi, F De Marchi, L Mazzini, C Bendotti - Brain Research Bulletin, 2023 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by the loss of motor neurons and neuromuscular impairment leading to …

Stem-cell-based therapy: the celestial weapon against neurological disorders

MA Zayed, S Sultan, HO Alsaab, SM Yousof, GI Alrefaei… - Cells, 2022 - mdpi.com
Stem cells are a versatile source for cell therapy. Their use is particularly significant for the
treatment of neurological disorders for which no definitive conventional medical treatment is …

Stem cell treatments for amyotrophic lateral sclerosis: a critical overview of early phase trials

SA Goutman, MG Savelieff, SA Sakowski… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of cortical,
brainstem, and spinal motor neurons; it causes progressive muscle weakness and atrophy …

Extracellular vesicles in amyotrophic lateral sclerosis

G McCluskey, KE Morrison, C Donaghy, F Rene… - Life, 2022 - mdpi.com
Amyotrophic Lateral Sclerosis is a progressive neurodegenerative disease and is the most
common adult motor neuron disease. The disease pathogenesis is complex with the …

Local Spinal Cord Injury Treatment Using a Dental Pulp Stem Cell Encapsulated H2S Releasing Multifunctional Injectable Hydrogel

AA Albashari, Y He, Y Luo, X Duan, J Ali… - Advanced …, 2024 - Wiley Online Library
Spinal cord injury (SCI) commonly induces nerve damage and nerve cell degeneration. In
this work, a novel dental pulp stem cells (DPSCs) encapsulated thermoresponsive injectable …