Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …

Microvascular network growth and remodeling are common denominators for most age-
related pathologies. For multiple pathologies (myocardial infarction, stroke, hypertension) …

Developing therapies aimed at manipulating microvascular remodeling requires a better
understanding of angiogenesis and how angiogenesis relates to other network remodeling …

Background: Lymphatic and blood microvascular systems play a coordinated role in the
regulation of interstitial fluid balance and immune cell trafficking during inflammation. The …

The gap between in vitro and in vivo assays has inspired biomimetic model development.
Tissue engineered models that attempt to mimic the complexity of microvascular networks …

Shear stress is recognized as a regulator of angiogenesis. However, the shear stress
experienced by the endothelial cells of capillary sprouts remains unknown. The objective of …

Lymphatic and blood microvascular networks play critical roles in the clearance of excess
fluid from local tissue spaces. Given the importance of these dynamics in inflammation …

A challenge in cancer research is the lack of physiologically responsive in vitro models that
enable tracking of cancer cells in tissue-like environments. A model that enables real-time …

Angiogenesis, defined as the growth of new blood vessels from pre-existing vessels,
involves endothelial cells, pericytes, smooth muscle cells, immune cells, and the …

Objective: Angiogenesis is the growth of new vessels from pre-existing vessels and
commonly associated with two modes: capillary sprouting and capillary splitting. Previous …