[HTML][HTML] Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review

CL Wainwright, MM Teixeira, DL Adelson… - Pharmacological …, 2022 - Elsevier
Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

Innovative bioactive nanofibrous materials combining medicinal and aromatic plant extracts and electrospinning method

N Stoyanova, N Nachev, M Spasova - Membranes, 2023 - mdpi.com
Since antiquity, humans have known about plants as a medicinal cure. Recently, plant
extracts are attracting more attention as a result of their natural origin and wide range of …

Chromatographic methods developed for the quantification of quercetin extracted from natural sources: systematic review of published studies from 2018 to 2022

D Carvalho, C Pinho, R Oliveira, F Moreira, AI Oliveira - Molecules, 2023 - mdpi.com
Quercetin (QUE) is the most widely used flavonoid for therapeutic purposes. To improve the
available knowledge about the properties of some natural products, determining the amount …

Analysis of 14 terpenoids and sterols and variety discrimination of Codonopsis Radix using ultra‐high‐performance liquid chromatography‐quadrupole‐time‐of‐flight …

W Li, X Xu, Z Tang, Y Guo, D Fei… - Journal of Separation …, 2023 - Wiley Online Library
Recently, we confirmed that the 95% ethanol‐extracted fraction of Codonopsis Radix, which
contains several triterpenoids and sterols, possesses pharmacological activities. However …

Simultaneous determination of flavonoids and anthraquinones in honey by using SPE-CE-LIF

X Yu, W Yu, X Zhang, Y Wang, S Wang, H Zhai - Analytical Biochemistry, 2021 - Elsevier
Based on advantages of capillary electrophoresis (CE), a new solid-phase extraction (SPE)
coupled with CE has been developed for preconcentration, enrichment and determination of …

In Vitro Induction of Apoptosis in Isolated Acute Myeloid Leukemia Cells: The Role of Anastatica hierochuntica Methanolic Extract

IM El-Garawani, AS Abd El-Gaber, NA Algamdi… - Metabolites, 2022 - mdpi.com
Anastatica hierochuntica L.(Cruciferae) has been known in Egyptian folk medicine as a
remedy for gastrointestinal disorders, diabetes and heart diseases. Despite the wide usage …

From relative to absolute stereochemistry of secondary metabolites: Applications in plant chemistry

R Pereda-Miranda, E Bautista… - Revista Brasileira de …, 2023 - Springer
Structural elucidation of specialized metabolites or natural plant products, especially the
stereochemical features of chiral bioactive metabolites, is the most important stage for all …

Antihypertensive effect of patulitrin and other constituents from Tagetes patula L. (French marigold) in acute L-NAME induced hypertensive rats

F Sadaf, R Saleem, RA Khan, U Ahmad… - Natural Product …, 2024 - Taylor & Francis
The work is aimed to evaluate the blood pressure reducing effect of constituents from
methanol extract and associated constituents of Tagetes patula flowers in normotensive and …

Chemical composition analysis and multi-index component content determination of compounds in goupi plaster based on UPLC–Q-exactive-MS and UPLC–MS/MS

Y Xue, T Guan, J Liu, J Wang, Z Yang, F Guan, W Li… - Chromatographia, 2024 - Springer
Objective This study sought to evaluate and validate a method for chemical composition
analysis and content determination of Goupi plaster components, a conventional …

Qualitative and quantitative analysis of chemical constituents in goupi plaster prepared by various extraction methods using UPLC-Q-Exactive-MS and UPLC-MS/MS

T Guan, R Wang, J Wang, Q Zhang, Z Liu, Z Yang… - Heliyon, 2024 - cell.com
Goupi plaster, a representative preparation of black plaster, has demonstrated promising
effects in treating knee osteoarthritis. However, high temperature used in traditional frying …