Tendon injury: from biology to tendon repair

G Nourissat, F Berenbaum, D Duprez - Nature Reviews Rheumatology, 2015 - nature.com
Tendon is a crucial component of the musculoskeletal system. Tendons connect muscle to
bone and transmit forces to produce motion. Chronic and acute tendon injuries are very …

Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis

E Gracey, A Burssens, I Cambré, G Schett… - Nature reviews …, 2020 - nature.com
Mechanical loading is an important factor in musculoskeletal health and disease. Tendons
and ligaments require physiological levels of mechanical loading to develop and maintain …

High-dimensional single-cell cartography reveals novel skeletal muscle-resident cell populations

L Giordani, GJ He, E Negroni, H Sakai, JYC Law… - Molecular cell, 2019 - cell.com
Adult tissue repair and regeneration require stem-progenitor cells that can self-renew and
generate differentiated progeny. Skeletal muscle regenerative capacity relies on muscle …

Periodontal ligament stem cells: current status, concerns, and future prospects

W Zhu, M Liang - Stem cells international, 2015 - Wiley Online Library
Periodontal ligament stem cells (PDLSCs), which reside in the perivascular space of the
periodontium, possess characteristics of mesenchymal stem cells and are a promising tool …

Pathogenesis of tendinopathies: inflammation or degeneration?

M Abate, K Gravare Silbernagel, C Siljeholm… - Arthritis research & …, 2009 - Springer
The intrinsic pathogenetic mechanisms of tendinopathies are largely unknown and whether
inflammation or degeneration has the prominent role is still a matter of debate. Assuming …

[HTML][HTML] Novel model of tendon regeneration reveals distinct cell mechanisms underlying regenerative and fibrotic tendon healing

K Howell, C Chien, R Bell, D Laudier, SF Tufa… - Scientific reports, 2017 - nature.com
To date, the cell and molecular mechanisms regulating tendon healing are poorly
understood. Here, we establish a novel model of tendon regeneration using neonatal mice …

Skeletal muscle differentiation of human iPSCs meets bioengineering strategies: perspectives and challenges

F Iberite, E Gruppioni, L Ricotti - NPJ Regenerative Medicine, 2022 - nature.com
Although skeletal muscle repairs itself following small injuries, genetic diseases or severe
damages may hamper its ability to do so. Induced pluripotent stem cells (iPSCs) can …

Structure‐function relationships in tendons: a review

M Benjamin, E Kaiser, S Milz - Journal of anatomy, 2008 - Wiley Online Library
The purpose of the current review is to highlight the structure‐function relationship of
tendons and related structures to provide an overview for readers whose interest in tendons …

[HTML][HTML] Conversion of mechanical force into TGF-β-mediated biochemical signals

T Maeda, T Sakabe, A Sunaga, K Sakai, AL Rivera… - Current Biology, 2011 - cell.com
Mechanical forces influence homeostasis in virtually every tissue [1, 2]. Tendon, constantly
exposed to variable mechanical force, is an excellent model in which to study the conversion …

Functional attachment of soft tissues to bone: development, healing, and tissue engineering

HH Lu, S Thomopoulos - Annual review of biomedical …, 2013 - annualreviews.org
Connective tissues such as tendons or ligaments attach to bone across a multitissue
interface with spatial gradients in composition, structure, and mechanical properties. These …