Mouse models to study dengue virus immunology and pathogenesis
RM Zellweger, S Shresta - Frontiers in immunology, 2014 - frontiersin.org
The development of a compelling murine model of dengue virus (DENV) infection has been
challenging, because DENV clinical isolates do not readily replicate or cause pathology in …
challenging, because DENV clinical isolates do not readily replicate or cause pathology in …
[HTML][HTML] Targets and strategies for vaccine development against dengue viruses
WH Wang, AN Urbina, CY Lin, ZS Yang… - Biomedicine & …, 2021 - Elsevier
Dengue virus (DENV) is a global health threat causing about half of the worldwide
population to be at risk of infection, especially the people living in tropical and subtropical …
population to be at risk of infection, especially the people living in tropical and subtropical …
Humanized mice in dengue research: a comparison with other mouse models
C Coronel-Ruiz, H Gutiérrez-Barbosa… - Vaccines, 2020 - mdpi.com
Dengue virus (DENV) is an arbovirus of the Flaviviridae family and is an enveloped virion
containing a positive sense single-stranded RNA genome. DENV causes dengue fever (DF) …
containing a positive sense single-stranded RNA genome. DENV causes dengue fever (DF) …
Can complementary prime-boost immunization strategies be an alternative and promising vaccine approach against dengue virus?
Dengue is one of the most important diseases transmitted by mosquitoes. Dengvaxia®, a
vaccine registered in several countries, cannot be administered to non-immune individuals …
vaccine registered in several countries, cannot be administered to non-immune individuals …
Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice
N Coconi-Linares, E Ortega-Dávila, M López-González… - Vaccine, 2013 - Elsevier
Dengue virus (DENV) is the causal agent of severe disease and, in some cases, mortality in
humans, but no licensed vaccines against dengue are available. An effective vaccine …
humans, but no licensed vaccines against dengue are available. An effective vaccine …
[HTML][HTML] A DNA vaccine candidate encoding the structural prM/E proteins elicits a strong immune response and protects mice against dengue-4 virus infection
A DNA vaccine expressing dengue-4 virus premembrane (prM) and envelope (E) genes
was produced by inserting these genes into a mammalian expression plasmid (pCI) …
was produced by inserting these genes into a mammalian expression plasmid (pCI) …
Dengue Virus and Vaccines: How Can DNA Immunization Contribute to This Challenge?
AMB Alves, SM Costa, PBA Pinto - Frontiers in medical technology, 2021 - frontiersin.org
Dengue infections still have a tremendous impact on public health systems in most countries
in tropical and subtropical regions. The disease is systemic and dynamic with broad range of …
in tropical and subtropical regions. The disease is systemic and dynamic with broad range of …
Combination of E-and NS1-derived DNA vaccines: the immune response and protection elicited in mice against DENV2
PBA Pinto, TAC Barros, LM Lima, AR Pacheco… - Viruses, 2022 - mdpi.com
The occurrence of dengue disease has increased radically in recent decades. Previously,
we constructed the pE1D2 and pcTPANS1 DNA vaccines encoding the DENV2 envelope …
we constructed the pE1D2 and pcTPANS1 DNA vaccines encoding the DENV2 envelope …
Germinal center reaction following cutaneous dengue virus infection in immune-competent mice
JC Yam-Puc, J García-Cordero… - Frontiers in …, 2015 - frontiersin.org
Dengue virus (DENV) has four serotypes, which can cause from asymptomatic disease to
severe dengue. Heterologous secondary infections have been associated to a greater risk of …
severe dengue. Heterologous secondary infections have been associated to a greater risk of …