Hyperhomocysteinemia (HHcy) is considered an independent risk factor for cardiovascular
disease, including ischemic heart disease, stroke, and peripheral vascular disease …

Background Dopamine replacement therapy by its precursor, L-3.4-dihydroxyphenylalanine
(L-DOPA), has been the treatment of choice for Parkinson's disease. However, the possible …

Diabetic patients routinely have elevated homocysteine levels, and due to increase in
oxidative stress, hyperhomocysteinemia is associated with increased mitochondrial …

Abstract Introduction: Neurotoxic homocysteine (Hcy) is thought to be an independent risk
factor for neurodegenerative diseases, including Alzheimer's disease. This study is to …

Neuronal cell death and its regulation have been extensively studied as an essential
process of both neurodevelopment and neurodegenerative conditions. However it is not …

The scientific literature contains a multitude of papers linking homocysteine to poor health.
Elevated homocysteine levels have been linked to cardiovascular disorders, an increased …

With this research we set out to develop a number of coumarin-based 'AND'logic
fluorescence probes that were capable of detecting a chosen analyte in the presence of …

Homocysteine has gathered considerable interest in recent years after being implicated in
the pathogenesis of various clinical conditions. It has been an elusive target with many …

Duchenne muscular dystrophy (DMD) results from null mutation of dystrophin, a membrane‐
associated structural protein that is expressed in skeletal muscle. Dystrophin deficiency …

In our previous study using iTRAQ technique we found that the level of calmodulin-
dependent protein kinase 2b (Camk2b) was lower in rats with hyperhomocysteinemia. We …