Lymph node metastasis informs prognosis and is a key factor in deciding further
management, particularly adjuvant chemotherapy. It is core to all contemporary staging …

Background The benefits of extensive lymph node dissection as performed in complete
mesocolic excision are still debated, although recent studies have shown an association …

Background: Timely diagnosis and classification of colorectal cancer (CRC) are hindered by
unsatisfactory clinical assays. Our aim was to construct a blood-based biomarker series …

The one-step nucleic acid amplification (OSNA) assay was initially developed for the
intraoperative assessment of sentinel lymph node metastases in breast cancer. This assay …

The tumour-stroma ratio (TSR) and tumour budding (TB) are two high-risk factors with
potential to be implemented in the next TNM classification. The aim of the current study was …

Background We previously reported that the one-step nucleic acid amplification (OSNA)
assay provided a judgment performance for colorectal cancer equivalent to a 2-mm-interval …

Purpose Surgery remains the mainstay of treatment for potentially curable colon cancer.
Otherwise, the surgical stress response might increase the likelihood of cancer …

One-step nucleic acid amplification (OSNA) is a rapid intraoperative molecular detection
technique for sentinel node assessment via the quantitative measurement of target …

Background Sentinel lymph node (SLN) mapping was reported to improve lymph node
staging in colon cancer. This study compares isosulfan blue (IB) with indocyanine green …

This review aims to describe the results of the most recent studies on the prognostic value of
TDs and highlight the impact of TDs on the staging and treatment of colorectal and gastric …