Gelatinases (matrix metalloproteinase-2 and-9) are enzymes from the matrix
metalloproteinases (MMPs) family, which are associated with collagen degradation. MMP-2 …

The pathogenesis of obesity-associated cardiovascular diseases begins long prior to the
presentation of a cardiovascular event. In both men and women, cardiovascular events, and …

Background: Preeclampsia (PE) is one of the leading causes of maternal and fetal morbidity
and mortality worldwide. Placental oxidative stress has been identified as a major pathway …

Ceramides are a group of sphingolipids located in the external plasma membrane layer and
act as messengers in cellular pathways such as inflammatory processes and apoptosis …

Background: Patients with preeclampsia demonstrate increases in placental leptin
production in midgestation, and an associated increase in late gestation plasma leptin …

Background Preeclampsia, especially preterm preeclampsia and early-onset preeclampsia,
is a life-threating pregnancy disorder, and the heterogeneity and complexity of preeclampsia …

Introduction: Preeclampsia (PE) is a gestational hypertensive disease with unclear
pathogenesis. This study aimed to identify the genes that play an important role in …

Preterm birth (historically defined as delivery before 37 weeks completed gestation)
represents a substantial global health problem and is responsible for more deaths under the …

Objective This study aimed to develop a blood test for the prediction of pre-eclampsia (PE)
early in gestation. We hypothesised that the longitudinal measurements of circulating …

Preeclampsia (PE) is an important research subject in obstetrics. Nevertheless, the
underlying mechanisms of PE remain elusive. PE-related expression datasets (GSE96983 …