Mechanisms and review of clinical evidence of variations in relative biological effectiveness in proton therapy
H Paganetti - International Journal of Radiation Oncology* Biology …, 2022 - Elsevier
Proton therapy is increasingly being used as a radiation therapy modality. There is
uncertainty about the biological effectiveness of protons relative to photon therapies as it …
uncertainty about the biological effectiveness of protons relative to photon therapies as it …
Comparison of particle beam therapy and stereotactic body radiotherapy for early stage non-small cell lung cancer: A systematic review and hypothesis-generating …
A Chi, H Chen, S Wen, H Yan, Z Liao - Radiotherapy and Oncology, 2017 - Elsevier
Purpose To assess hypo-fractionated particle beam therapy (PBT)'s efficacy relative to that
of photon stereotactic body radiotherapy (SBRT) for early stage (ES) non-small cell lung …
of photon stereotactic body radiotherapy (SBRT) for early stage (ES) non-small cell lung …
[HTML][HTML] Distributed learning: developing a predictive model based on data from multiple hospitals without data leaving the hospital–a real life proof of concept
A Jochems, TM Deist, J Van Soest, M Eble… - Radiotherapy and …, 2016 - Elsevier
Purpose One of the major hurdles in enabling personalized medicine is obtaining sufficient
patient data to feed into predictive models. Combining data originating from multiple …
patient data to feed into predictive models. Combining data originating from multiple …
[HTML][HTML] Infrastructure and distributed learning methodology for privacy-preserving multi-centric rapid learning health care: euroCAT
Abstract Machine learning applications for personalized medicine are highly dependent on
access to sufficient data. For personalized radiation oncology, datasets representing the …
access to sufficient data. For personalized radiation oncology, datasets representing the …
Radiomics and dosiomics signature from whole lung predicts radiation pneumonitis: A model development study with prospective external validation and decision …
Purpose Radiation pneumonitis (RP) is one of the common side effects of radiation therapy
in the thoracic region. Radiomics and dosiomics quantify information implicit within medical …
in the thoracic region. Radiomics and dosiomics quantify information implicit within medical …
[HTML][HTML] ACE inhibition attenuates radiation-induced cardiopulmonary damage
SJ van der Veen, G Ghobadi, RA de Boer… - Radiotherapy and …, 2015 - Elsevier
Background and purpose In thoracic irradiation, the maximum radiation dose is restricted by
the risk of radiation-induced cardiopulmonary damage and dysfunction limiting tumor …
the risk of radiation-induced cardiopulmonary damage and dysfunction limiting tumor …
Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation
SL Tucker, A Liu, D Gomez, LL Tang, P Allen… - Radiotherapy and …, 2016 - Elsevier
Background and purpose To determine whether the impact of heart dose on early overall
survival (OS) reported in RTOG 0617 could be confirmed in an independent cohort …
survival (OS) reported in RTOG 0617 could be confirmed in an independent cohort …
A prospective study comparing the predictions of doctors versus models for treatment outcome of lung cancer patients: a step toward individualized care and shared …
Abstract Background Decision Support Systems, based on statistical prediction models,
have the potential to change the way medicine is being practiced, but their application is …
have the potential to change the way medicine is being practiced, but their application is …
Modeling the risk of radiation-induced lung fibrosis: Irradiated heart tissue is as important as irradiated lung
Purpose We used normal tissue complication probability (NTCP) modeling to explore the
impact of heart irradiation on radiation-induced lung fibrosis (RILF). Materials and methods …
impact of heart irradiation on radiation-induced lung fibrosis (RILF). Materials and methods …
The effect of different comorbidities on survival of non-small cells lung cancer patients
M Iachina, E Jakobsen, H Møller, M Lüchtenborg… - Lung, 2015 - Springer
Purpose Primary lung cancer is one of the most common types of cancers. Comorbidity has
been shown to be a negative prognostic factor in the overall lung cancer population. The …
been shown to be a negative prognostic factor in the overall lung cancer population. The …